ReviewJournal of the colleges of medicine of South Africa2025
Association of hyperkalaemia with electrocardiographic changes at a tertiary centre in South Africa.
Review in Journal of the colleges of medicine of South Africa, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Background: Hyperkalaemia is a common electrolyte disorder in hospitalised patients and is associated with fatal cardiac arrhythmias. In sub-Saharan Africa, there is a paucity of data regarding the prevalence and type of electrocardiographic (ECG) changes in patients who have hyperkalaemia. Methods: A retrospective descriptive study was conducted at Tygerberg Hospital over a one-year period in 2019. Adult patients with hyperkalaemia of ≥ 5.5 mmol/L and associated ECG changes 3 h before or after documented laboratory hyperkalaemia were included. Spearman correlation coefficients and multilinear regression were used to identify correlations and associations, respectively, between serum potassium concentrations ([K Results: Of 344 patients who had hyperkalaemia and an associated ECG, 55% had ECG changes. These patients were older (60 years vs. 53 years, Conclusion: The overall prevalence of ECG changes due to hyperkalaemia was only 55%. Contribution: It is essential for clinicians to recognise that the ECG changes during hyperkalaemia may have limited screening value.
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