Evidence map›Paper›PMID 40951595›Full record

ArticleAlzheimer's & dementia (New York, N. Y.)

Low intrinsic capacity is associated with a blunted exercise-induced cognitive enhancement in physically active middle-aged and older adults.

Brandon A Yates, Ariela R Orkaby, Jakob L Vingren, Lawrence E Armstrong

Abstract read
In one paragraph

Article in Alzheimer's & dementia (New York, N. Y.). The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Brandon A YatesDepartment of Physical Medicine & Rehabilitation Harvard Medical School Cambridge Massachusetts USA.ORCID https://orcid.org/0000-0003-2724-1376
Ariela R OrkabyNew England Geriatric Research, Education, and Clinical Center (GRECC) VA Boston Healthcare System Jamaica Plain Massachusetts USA.
Jakob L VingrenApplied Physiology Laboratory Department of Kinesiology Health Promotion, and Recreation University of North Texas Denton Texas USA.
Lawrence E ArmstrongHuman Performance Laboratory University of Connecticut Storrs Connecticut USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionThe World Health Organization supports intrinsic capacity (IC) as a framework for assessing and monitoring an older person's cognitive health. Low IC is associated with higher dementia risk. Regular exercise participation improves cognitive health, reduces dementia risk, and may increase IC. However, the long-term chronic brain benefits of regular exercise training are dependent upon the effectiveness of single exercise bouts to augment cognition. Yet, how IC influences the magnitude of improvement following a single exercise bout has not been elucidated.

methodsA convenience sampling of 40 physically active adults (55 ± 6 years; mean ± SD) with a body mass index ≥ 24.9 kg/m

resultsParticipants had similar DISCUSSION: Low IC is associated with a blunted acute exercise-induced cognitive enhancement in mid to late adulthood. Future research is justified to determine the physiological mechanisms underpinning this novel finding. Highlights: Adults with overweight/obesity show cognitive gains after endurance exercise.Poor locomotor function limits cognitive gains from exercise in overweight adults.IC better predicts exercise-related cognitive gains than cognition.

Indexed as

aerobic exerciseexecutive functionfrailtygait speedoverweight, and obesityresilience

Identifiers

PMID40951595
PMCPMC12426311

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.