ArticleFood science & nutrition2025
Novel Insights Into the Causal Association Between Dietary Factors and Risk of Urinary Calculus: A Multivariate and Two-Step Mendelian Randomization Analysis.
Article in Food science & nutrition, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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1 citing paper in PubMed.
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Authors and funding
10 authors.
Funding
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Abstract
Previous observational studies preliminarily unveiled dietary habits that are associated with urinary calculus (UC). However, the causal association remained unclear. This study employed two-sample Mendelian randomization (MR) to assess the causal effects of dietary factors on UC using genome-wide association data. Multivariable MR (MVMR) was applied to identify independent dietary influences, and two-step MR explored mediation by 30 common biomarkers. Genetically predicted intake of alcohol, coffee (including decaffeinated, instant, and ground coffee), psychoactive drinks, tea, fruits (including dried fruit), and preferences for coffee without sugar, fruit, and white wine were inversely associated with calculus of the kidney and ureter (all
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