Evidence map›Paper›PMID 40951588›Full record

ReviewFood science & nutrition2025

Selenium-Polysaccharides: Structural Characterization, Biological Activities, and Emerging Applications.

Shahidin, Yilong Wu, Yan Wang, Taixia Chen, Pengyan Zhu, Xuanjun Wang, Chengting Zi

Abstract readReview
In one paragraph

Review in Food science & nutrition, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Review
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

ShahidinKey Laboratory of Pu-erh Tea Science, Ministry of Education, College of Food Science and Technology Yunnan Agricultural University Kunming China.ORCID https://orcid.org/0009-0005-4298-8568
Yilong WuKey Laboratory of Pu-erh Tea Science, Ministry of Education, College of Food Science and Technology Yunnan Agricultural University Kunming China.
Yan WangKey Laboratory of Pu-erh Tea Science, Ministry of Education, College of Food Science and Technology Yunnan Agricultural University Kunming China.
Taixia ChenKey Laboratory of Pu-erh Tea Science, Ministry of Education, College of Food Science and Technology Yunnan Agricultural University Kunming China.
Pengyan ZhuKey Laboratory of Pu-erh Tea Science, Ministry of Education, College of Food Science and Technology Yunnan Agricultural University Kunming China.
Xuanjun WangKey Laboratory of Pu-erh Tea Science, Ministry of Education, College of Food Science and Technology Yunnan Agricultural University Kunming China.
Chengting ZiKey Laboratory of Pu-erh Tea Science, Ministry of Education, College of Food Science and Technology Yunnan Agricultural University Kunming China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Selenium-polysaccharides (SePs) are an emerging class of bioactive compounds formed by incorporating inorganic Se into polysaccharides, exhibiting enhanced biological activity compared to inorganic Se or isolated polysaccharides. The extraction of SePs from Se-enriched sources and the selenylation of polysaccharides are crucial for improving their biological activities, leading to structural variations that contribute to diverse biological effects. Structural variations in SePs, influenced by the incorporation of Se at specific positions or the formation of seleno-groups, play a key role in their biological effects. SePs have demonstrated antioxidant, anti-cancer, immune-regulating, anti-inflammatory, and other health benefits, making them promising candidates for nutraceutical applications. However, several areas remain underexplored in existing reviews, such as the dynamics of Se and its biosynthetic pathways in plants, as well as the structure-activity relationships and emerging applications of SePs. This study aims to investigate these biosynthetic pathways, structure-activity relationships, and the potential therapeutic and industrial applications of SePs. It highlights their potential in the food and health sectors, while also emphasizing the need for further research in these areas.

Indexed as

biological activitiesbiosynthetic pathwayemerging applicationspreparationselenium‐polysaccharidesstructural characterizationstructure–activity relationship

Identifiers

PMID40951588
PMCPMC12423554

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.