Evidence map›Paper›PMID 40951488›Full record

SynthesisNarra J2025

Comparative efficacy of solifenacin and tamsulosin in alleviating stent-related symptoms: A systematic review and meta-analysis.

Dianita H Harahap, Kharisma P Adhyatma, Elbert Elbert, Felix Khosasi, Muhammad H Warli

Abstract readSystematic ReviewMeta-AnalysisComparative Study
In one paragraph

Synthesis in Narra J, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Dianita H HarahapDivision of Urology, Department of Surgery, Faculty of Medicine, Universitas Sumatera Utara, Medan, Indonesia.
Kharisma P AdhyatmaDivision of Urology, Department of Surgery, Faculty of Medicine, Universitas Sumatera Utara, Medan, Indonesia.
Elbert ElbertFaculty of Medicine, Universitas Sumatera Utara, Medan, Indonesia.
Felix KhosasiFaculty of Medicine, Universitas Sumatera Utara, Medan, Indonesia.
Muhammad H WarliDivision of Urology, Department of Surgery, Faculty of Medicine, Universitas Sumatera Utara, Medan, Indonesia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Ureteral stents, commonly used in urology, can cause side effects affecting patient quality of life. However, studies on managing lower urinary tract symptoms showed inconsistencies due to the use of various alpha-blockers and antimuscarinic drugs. The aim of this study was to evaluate the effectiveness of combining tamsulosin and solifenacin therapy compared to tamsulosin and solifenacin monotherapy for treating stent-related symptoms. Randomized controlled trials assessing tamsulosin, solifenacin, or their combination for stent-related symptoms treatment were identified through a comprehensive search of four databases (PubMed, Scopus, Web of Science, and Cochrane) from January 2018 to December 2023. Ureteral stent symptom questionnaire (USSQ), international prostate symptom score (IPSS), visual analog scale (VAS), and quality of life (QoL) were pooled for meta-analysis. Eleven studies with a total of 1,627 patients were included in the quantitative analysis. Solifenacin significantly improved urinary symptoms (MD: 15.31; 95%CI: 0.36-30.26;

Indexed as

Lower Urinary Tract SymptomsSolifenacin SuccinateStentsTamsulosinHumansMaleMuscarinic AntagonistsQuality of LifeRandomized Controlled Trials as TopicTreatment OutcomeMuscarinic AntagonistsSolifenacin SuccinateTamsulosinQoLsolifenacinstent-related symptomstamsulosinUreteral stent

Identifiers

PMID40951488
PMCPMC12425523

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.