Evidence map›Paper›PMID 40951405›Full record

ArticleFrontiers in public health2025

Exploring the willingness to pay for HPV vaccines and price sensitivity among Chinese college students: the impact of health literacy and vaccine hesitancy.

Yuan Li, Hiromi Kawasaki, Zhengai Cui, Sae Nakaoka, Yingai Cui, Md Moshiur Rahman

Abstract read
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Article in Frontiers in public health, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Yuan LiGraduate School of Biomedical and Health Sciences, Hiroshima University, Hiroshima, Japan.
Hiromi KawasakiGraduate School of Biomedical and Health Sciences, Hiroshima University, Hiroshima, Japan.
Zhengai CuiSchool of Humanities and Management, Guangdong Medical University, Dongguan, China.
Sae NakaokaGraduate School of Biomedical and Health Sciences, Hiroshima University, Hiroshima, Japan.
Yingai CuiSchool of Nursing, Guangdong Medical University, Dongguan, China.
Md Moshiur RahmanGraduate School of Biomedical and Health Sciences, Hiroshima University, Hiroshima, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Human papillomavirus (HPV) infection constitutes a substantial public health challenge in China. Despite proven vaccine efficacy, coverage remains critically low among high-risk sexually active college students. Out-of-pocket payment requirements contribute to the intention-behavior gap, while health literacy (HL) and vaccine hesitancy (VH) influence payment decisions. This study aims to directly quantify Chinese college students' willingness to pay (WTP) and price sensitivity, examining HL and VH as key determinants. Methods: A convenience sample of 4,928 students at Guangdong Medical University in Dongguan, China was selected to complete a cross-sectional online survey (June 16-July 16, 2024) on the "Wenjuanxing" platform. We assessed socioeconomic status, HPV knowledge, HL, VH, and WTP through the survey and applied the van Westendorp price sensitivity meter (PSM) to quantify HPV vaccine price sensitivity. Results: A total of 67.6% of the participants expressed a WTP for an out-of-pocket HPV vaccine, with 87.2% preferring nine-valent vaccines. Key factors identified included monthly expenses, medical insurance, HPV knowledge, HL, and the VH items' perceived necessity, importance, and vaccine safety. The van Westendorp PSM indicated that the market prices of the nine-valent vaccines exceeded the college students' acceptable price ranges. Conclusion: Examination of HL and VH provided a valuable framework for understanding the WTP for HPV vaccines. The van Westendorp PSM confirmed that the price sensitivity of the nine-valent HPV vaccine exceeded its affordability. Integrating vaccines into medical insurance, implementing targeted tiered subsidies (e.g., an optimal subsidy of 269.81 CNY, or at least 126.20 CNY), and conducting tailored education addressing HL/VH should be prioritized as potential solutions.

Indexed as

Health ExpendituresHealth LiteracyPapillomavirus InfectionsPapillomavirus VaccinesStudentsVaccination HesitancyAdolescentAdultChinaCross-Sectional StudiesFemaleHealth Knowledge, Attitudes, PracticeHumansMaleSurveys and QuestionnairesUniversitiesPapillomavirus Vaccinescollege studentshealth literacyHPV vaccinevaccine hesitancyvan Westendorp PSMwillingness to pay

Identifiers

PMID40951405
PMCPMC12425919

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.