ArticleFrontiers in oncology2025
Synergistic antiproliferative and pro-apoptotic effects of
Article in Frontiers in oncology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Introduction: Breast cancer is the most prevalent malignancy among women worldwide, with triple-negative breast cancer (TNBC) posing significant therapeutic challenges due to its aggressive nature and lack of targeted treatments. Natural compounds such as Methods: This study evaluates the synergistic effects of PA and BV on breast cancer cells, focusing on proliferation, apoptosis, and invasion. MCF-7 and MDA-MB-231 breast cancer cells were treated with varying concentrations (0-500 µg/mL) of PA, BV, and their combination. Cytotoxicity was assessed via the MTT assay, and the IC50 values were determined using GraphPad Prism. Colony formation, phase contrast microscopy, Acridine Orange/Ethidium Bromide (AO/EB) staining, transwell invasion, and Western blot assays were performed to evaluate proliferation, apoptosis, and invasion. Statistical significance was determined using one-way ANOVA. Result and discussion: The combination of PA and BV significantly enhanced cytotoxicity, with IC
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.