Evidence map›Paper›PMID 40951315›Full record

ArticleFrontiers in cellular and infection microbiology2025

CRISPR typing and phage content of colonizing Group B

Sarah Shabayek, Dorina Haider, Verena Vogel, Uzma Basit Khan, Dorota Jamrozy, Elita Jauneikaite, Kirsty LeDoare, Stephen Bentley, Barbara Spellerberg

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In one paragraph

Article in Frontiers in cellular and infection microbiology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0cells of the map it votes in
0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Sarah ShabayekDepartment of Microbiology and Immunology, Faculty of Pharmacy, Suez Canal University, Ismailia, Egypt.
Dorina HaiderInstitute of Medical Microbiology and Hygiene, University Hospital Ulm, Ulm, Germany.
Verena VogelInstitute of Medical Microbiology and Hygiene, University Hospital Ulm, Ulm, Germany.
Uzma Basit KhanParasites and Microbes, Wellcome Sanger Institute, Hinxton, United Kingdom.
Dorota JamrozyParasites and Microbes, Wellcome Sanger Institute, Hinxton, United Kingdom.
Elita JauneikaiteDepartment of Metabolism, Digestion and Reproduction, Institute of Reproduction and Developmental Biology, Imperial College London, London, United Kingdom.
Kirsty LeDoareCentre for Neonatal and Paediatric Infection, Maternal and Neonatal Vaccinology Group, City St. Georges University of London, London, United Kingdom.
Stephen BentleyParasites and Microbes, Wellcome Sanger Institute, Hinxton, United Kingdom.
Barbara SpellerbergInstitute of Medical Microbiology and Hygiene, University Hospital Ulm, Ulm, Germany.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Methods: The current study analyzes the structure and diversity of the clustered regularly interspaced palindromic repeat (CRISPR)-associated (Cas) system and phage content in colonizing GBS isolates collected from healthy pregnant women from Ismailia, Egypt. The isolates were characterized by whole-genome sequencing within the global JUNO project. Results: CRISPR arrays and phages were detected in a vast majority of GBS isolates. A strong congruence was observed between multilocus sequence typing (MLST), CRISPR profile, and phage content. Region-specific sequence types (STs) observed only in Africa were distinguishable from other lineages. Conclusions: CRISPR typing is a promising low-cost tool for investigating the population structure of GBS clones, particularly in middle- and low-income countries.

Indexed as

BacteriophagesCarrier StateClustered Regularly Interspaced Short Palindromic RepeatsStreptococcal InfectionsStreptococcus agalactiaeAdultEgyptFemaleHumansMultilocus Sequence TypingPregnancyVaginaWhole Genome SequencingAfricaCRISPRepidemiologyGBS (Group B Streptococcus)phage (bacteriophage)

Identifiers

PMID40951315
PMCPMC12423071

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.