Evidence map›Paper›PMID 40951307›Full record

ArticleFrontiers in cellular and infection microbiology2025

The RNA-binding protein ProQ directly binds and regulates virulence genes in enterohemorrhagic

Ye Qian, Chenguang Zheng, Runhua Han

Abstract read
In one paragraph

Article in Frontiers in cellular and infection microbiology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Ye Qian *School of Basic Medical Sciences, North China University of Science and Technology, Tangshan, China.
Chenguang Zheng *School of Public Health, North China University of Science and Technology, Tangshan, China.
Runhua HanDepartment of Chemistry, University of Manitoba, Winnipeg, MB, Canada.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

ProQ has recently emerged as a major post-transcriptional regulator in bacteria through directly binding to diverse mRNAs and small regulatory RNAs (sRNAs). However, the impact of ProQ in many pathogenic bacteria remains poorly understood. In this study, we investigated the role of ProQ in enterohaemorrhagic

Indexed as

Escherichia coli O157Escherichia coli ProteinsGene Expression Regulation, BacterialRNA-Binding ProteinsVirulence FactorsBacterial AdhesionEscherichia coli InfectionsGene DeletionGenomic IslandsHumansPhosphoproteinsProtein BindingRNA, BacterialRNA, MessengerRNA, Small UntranslatedVirulenceEscherichia coli ProteinsLEE protein, E coliPhosphoproteinsRNA, BacterialRNA-Binding ProteinsRNA, MessengerRNA, Small UntranslatedVirulence FactorsEHECLEEO157:H7ProQRNA binding proteinRNA regulationsmall regulatory RNAvirulence gene regulation

Identifiers

PMID40951307
PMCPMC12426089

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.