Evidence map›Paper›PMID 40951301›Full record

ArticleResearch square2025

PIF4-mediated thermomorphogenesis relies on its oligomerization ability, not DNA-binding or transactivation activity.

Haibo Xiong, Abhishesh Bajracharya, Ranjeeta Odari, Eden E Bayer, Alyssa Stoner, Anupa Wasti, Jing Xi, Scott R Baerson, Yongjian Qiu

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In one paragraph

Article in Research square, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

9 authors.

Haibo XiongDepartment of Biology, University of Mississippi, University, MS 38677, USA.
Abhishesh BajracharyaDepartment of Biology, University of Mississippi, University, MS 38677, USA.
Ranjeeta OdariDepartment of Biology, University of Mississippi, University, MS 38677, USA.
Eden E BayerDepartment of Biology, University of Mississippi, University, MS 38677, USA.ORCID 0000-0003-3621-4097
Alyssa StonerDepartment of Biology, University of Mississippi, University, MS 38677, USA.
Anupa WastiDepartment of Biology, University of Mississippi, University, MS 38677, USA.
Jing XiNatural Products Utilization Research Unit, U.S. Department of Agriculture, Agricultural Research Service, University, MS 38677, USA.
Scott R BaersonNatural Products Utilization Research Unit, U.S. Department of Agriculture, Agricultural Research Service, University, MS 38677, USA.
Yongjian QiuDepartment of Biology, University of Mississippi, University, MS 38677, USA.ORCID 0000-0002-1799-6305

Funding

Laser spectroscopic instrumentation for isotopic sensing of biogenic Nitric OxideR21GM103460 · NIGMS · PRINCETON UNIVERSITY · PI WYSOCKI, GERARD · 2012 to 2012
$190k
NIGMS NIH HHS R21 GM103460
6 · The paper itself

Abstract

Plants tailor their architecture to warm ambient temperatures through the central thermosensory transcription factor PHYTOCHROME-INTERACTING FACTOR 4 (PIF4), yet the sequence features that confer this activity remain poorly defined. Here, we combine targeted mutagenesis, phase-separation assays, and transgenic complementation to dissect how structured and disordered regions of PIF4 contribute to its function in thermomorphogenesis. A long N-terminal intrinsically disordered region (IDR) enables PIF4 to form gel-like condensates in vitro and

Indexed as

Basic helix-loop-helix (bHLH)DNA-binding domain (DBD)Intrinsically disordered region (IDR)Phase separationPhytochrome-Interacting Factor 4 (PIF4)ThermomorphogenesisTranscriptional activation domain (TAD)

Identifiers

PMID40951301
PMCPMC12425084

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.