Evidence map›Paper›PMID 40951274›Full record

ArticleResearch square2025

A common DNA deletion altering the 3'UTR of

Katie Ko, Kieran Tebben, Tsarasoa Andrianinarivomanana, Agnes Orban, Janne Grünebast, Virak Eng, Rotha Eam, Nimol Khim, Lionel Feufack-Donfack, Jeremy Salvador and 5 more

Abstract readPreprint
In one paragraph

Article in Research square, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

15 authors.

Katie KoUniversity of Maryland, Baltimore.ORCID 0009-0006-4116-1443
Kieran TebbenUniversity of Maryland, Baltimore.ORCID 0000-0001-8866-7667
Tsarasoa AndrianinarivomananaInstitut Pasteur du Cambodge.
Agnes OrbanInstitut Pasteur du Cambodge.
Janne GrünebastUniversity of Maryland, Baltimore.ORCID 0009-0005-1329-4241
Virak EngInstitut Pasteur du Cambodge.
Rotha EamInstitut Pasteur du Cambodge.
Nimol KhimInstitut Pasteur du Cambodge.
Lionel Feufack-DonfackInstitut Pasteur du Cambodge.
Jeremy SalvadorInstitut Pasteur du Cambodge.
Juliana SáNational Institute of Allergy and Infectious Diseases.ORCID 0000-0003-3813-8104
Thomas WellemsNational Institute of Allergy and Infectious Diseases.ORCID 0000-0003-3899-8454
Dysoley LekCentre for Parasitology, Entomology and Malaria Control.
Jean PopoviciInstitut Pasteur du Cambodge.ORCID 0000-0002-3135-1175
David SerreUniversity of Maryland, Baltimore.ORCID 0000-0002-2446-9095

Funding

Rigorous Assessment of P. vivax Relapses and Primaquine Efficacy for Radical CureR01AI146590 · NIAID · UNIVERSITY OF MARYLAND BALTIMORE · PI SERRE, DAVID · 2020 to 2024
$3.0M
Extent, dynamics and mechanisms of Plasmodium vivax immune evasion caused by PvDBP gene amplificationR01AI173171 · NIAID · INSTITUT PASTEUR DU CAMBODGE · PI Eugenia Lo, Jean POPOVICI · 2023 to 2026
$2.4M
Comprehensive characterization of the genetic factors and the host immune response associated to protection from clinical Plasmodium vivax malariaR01AI175134 · NIAID · INSTITUT PASTEUR DU CAMBODGE · PI TINEKE CANTAERT, Jean POPOVICI · 2023 to 2026
$2.3M
Leveraging access to parasite natural diversity to identify Plasmodium vivax culture-adaptable strain.R61AI187100 · NIAID · INSTITUT PASTEUR DU CAMBODGE · PI Jean POPOVICI · 2025 to 2026
$533k
NIAID NIH HHS R01 AI146590NIAID NIH HHS R01 AI173171NIAID NIH HHS R01 AI175134NIAID NIH HHS R61 AI187100
6 · The paper itself

Abstract

Artemisinin-combination therapies (ACTs) are now recommended for the treatment of uncomplicated malaria caused by

Identifiers

PMID40951274
PMCPMC12425083

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.