ArticleResearch square2025
ID2 secures cDC1 specification by antagonizing E proteins at a pleiotropic
Feiya Ou, Tian-Tian Liu, Siling Du, Jing Chen, Alyssa R Koch, Magdalena Kraft, Theresa L Murphy, Kenneth M Murphy
Abstract readPreprint
In one paragraphArticle in Research square, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
2 · The registryThe trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
3 · Its place in the literatureWho cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
4 · The recordCorrections and comments
5 · Who and what moneyAuthors and funding
8 authors.
Feiya OuDepartment of Pathology and Immunology, Washington University in St. Louis School of Medicine, St. Louis, MO, USA.ORCID 0000-0001-8289-4025 Tian-Tian LiuDepartment of Pathology and Immunology, Washington University in St. Louis School of Medicine, St. Louis, MO, USA.ORCID 0000-0001-9377-9938 Siling DuDepartment of Pathology and Immunology, Washington University in St. Louis School of Medicine, St. Louis, MO, USA.
Jing ChenDepartment of Pathology and Immunology, Washington University in St. Louis School of Medicine, St. Louis, MO, USA.
Alyssa R KochDepartment of Pathology and Immunology, Washington University in St. Louis School of Medicine, St. Louis, MO, USA.
Magdalena KraftDepartment of Pathology and Immunology, Washington University in St. Louis School of Medicine, St. Louis, MO, USA.
Theresa L MurphyDepartment of Pathology and Immunology, Washington University in St. Louis School of Medicine, St. Louis, MO, USA.
Kenneth M MurphyDepartment of Pathology and Immunology, Washington University in St. Louis School of Medicine, St. Louis, MO, USA.ORCID 0000-0002-3505-9630 Funding
Molecular Basis of cDC1 DevelopmentR01AI162643 · NIAID · WASHINGTON UNIVERSITY · PI MURPHY, KENNETH M · 2022 to 2025
$2.8MFunction of Wdfy4 in cross-presentation and immunityR01AI150297 · NIAID · WASHINGTON UNIVERSITY · PI MURPHY, KENNETH M · 2019 to 2023
$2.5MUnderstanding the Mechanisms of DC Licensing in CD8 T Cell PrimingR01CA248919 · NCI · WASHINGTON UNIVERSITY · PI MURPHY, KENNETH M · 2021 to 2025
$2.3MTranscriptional basis of embryonic macrophage developmentR21AI163421 · NIAID · WASHINGTON UNIVERSITY · PI MURPHY, KENNETH M · 2022 to 2023
$430kNCI NIH HHS R01 CA248919NIAID NIH HHS R01 AI150297NIAID NIH HHS R01 AI162643NIAID NIH HHS R21 AI163421
6 · The paper itselfAbstract
The transcriptional regulator ID2 is required for type 1 classical dendritic cell (cDC1) specification, yet the mechanism has remained obscure. We previously identified the
Identifiers
PMID40951272
PMCPMC12425045
What OpenQuestion holds
Textmetadata
LicenceCC BY
Read underepoch 390