Evidence map›Paper›PMID 40951267›Full record

ArticleResearch square2025

Differential Associations of Childhood Abuse and Neglect with Neural Responses to Social Reward and Punishment in Adults with Anxiety or Depression.

Isabella Spaulding, Murray Stein, Charles Taylor

Abstract readPreprint
PubMed Full text at PMC Publisher
In one paragraph

Article in Research square, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

3 authors.

Isabella SpauldingSan Diego State University/University of California, San Diego.
Murray SteinUniversity of California San Diego.ORCID https://orcid.org/0000-0001-9564-2871
Charles TaylorUniversity of California San Diego.

Funding

Novel Behavioral Intervention to Target Social Reward Sensitivity and AttachmentR33MH113769 · NIMH · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI TAYLOR, CHARLES · 2020 to 2022
$2.2M
Novel Behavioral Intervention to Target Social Reward Sensitivity and AttachmentR61MH113769 · NIMH · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI TAYLOR, CHARLES · 2017 to 2018
$1.5M
NIMH NIH HHS R33 MH113769NIMH NIH HHS R61 MH113769
6 · The paper itself

Abstract

Childhood adversity increases risk for impaired social functioning later in life; however, neural pathways delineating this association are poorly understood. Different types of adverse interpersonal experiences (i.e., abuse, neglect) may impact neural pathways distinctly, resulting in unique consequences on social motivation and behavior in adulthood. Here, we investigated neural responses during the anticipation of social reward and punishment and their associations with childhood abuse and neglect in adults with a depressive and/or anxiety disorder and social impairment. Participants (

Identifiers

PMID40951267
PMCPMC12425085

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.