Evidence map›Paper›PMID 40951253›Full record

ArticleCureus2025

Activated PI3K Delta Syndrome: A Case Presentation and Literature Review.

Angélica López Méndez, Airam A Arias Villaverde, Abraham P Sánchez López, Elizabeth Gloria Méndez, María R Hernández Zamora, Alesha Ramírez Lobato, María F Aguirre Quintero, Emilio Mondragón Rosas, José Emiliano González Flores

Abstract readCase Reports
PubMed Full text at PMC Publisher
In one paragraph

Article in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Angélica López MéndezPediatric Nephrology, Instituto Nacional de Pediatría (INP), Mexico City, MEX.
Airam A Arias VillaverdeSchool of Medicine and Health Sciences, Tecnológico de Monterrey Mexico City Campus, Mexico City, MEX.
Abraham P Sánchez LópezMedical Genetics, Iztacalco Pediatric Hospital, Mexico City, MEX.
Elizabeth Gloria MéndezSchool of Medicine, Panamerican University, Mexico City, MEX.
María R Hernández ZamoraPediatric Gastroenterology and Nutrition, Instituto Mexicano del Seguro Social, Centro Médico Nacional Siglo XXI, Mexico City, MEX.
Alesha Ramírez LobatoSchool of Medicine and Health Sciences, Tecnológico de Monterrey Mexico City Campus, Mexico City, MEX.
María F Aguirre QuinteroSchool of Medicine and Health Sciences, Tecnológico de Monterrey Mexico City Campus, Mexico City, MEX.
Emilio Mondragón RosasSchool of Medicine and Health Sciences, Tecnológico de Monterrey Mexico City Campus, Mexico City, MEX.
José Emiliano González FloresSchool of Medicine and Health Sciences, Tecnológico de Monterrey Mexico City Campus, Mexico City, MEX.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Activated PI3K delta syndrome (APDS) is a rare primary immunodeficiency caused by gain-of-function (GOF) mutations in

Indexed as

activated pi3k delta syndromegenetic mutationspi3kpik3r1 geneprimary immunodeficiency disease

Identifiers

PMID40951253
PMCPMC12424517

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.