ArticleCureus2025
Simultaneous Maxillofacial, Abdominal, and Bone Marrow Involvement in a Pediatric Patient With Epstein-Barr Virus-Associated Burkitt Lymphoma: A Case From India.
Article in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Authors and funding
6 authors.
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Abstract
Burkitt lymphoma is a rare and aggressive B-cell origin non-Hodgkin lymphoma, which has been classified as a poorly differentiated lymphocytic lymphoma. Three major subtypes of Burkitt lymphoma have been identified, namely endemic, sporadic, and immunodeficiency-associated. While an abdominal (ileocecal) mass is the most common presentation of Burkitt lymphoma in sporadic populations, including the Indian subcontinent, involvement of the face/jaw/sinuses/ovaries is considered to be extremely rare. We present the case of a three-year-old female child who presented with progressive, painless, bilateral cheek swelling with facial and periorbital puffiness and abdominal distension, which was associated with a high-grade fever and significant weight loss for 20 days. The simultaneous involvement of solid organs of the abdomen and face is a very rare presentation in the Indian population. Diagnosis was confirmed by fine needle aspiration cytology (FNAC) of cervical lymph nodes and immunohistochemistry (IHC) of bone marrow biopsy. The patient was diagnosed with Stage 4 Burkitt lymphoma. Extra-abdominal involvement at presentation, particularly of the facial bones or sinuses, is uncommon in the Indian setting. This highlights the variety of Burkitt clinical presentations in India and the significance of early diagnosis.
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