Evidence map›Paper›PMID 40951207›Full record

ArticleCureus2025

Severity of Ascending Aortic Degeneration in Patients With Chronic Obstructive Pulmonary Disease.

Essi Pirskanen, Mona Laaksonen, Trina Chen, Ivana Kholova, Otso Arponen, Petteri Kauhanen, Aada Lattu, Timo Paavonen, Ari Mennander

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Essi PirskanenDepartment of Cardiothoracic Surgery, Tampere University, Tampere, FIN.
Mona LaaksonenDepartment of Cardiothoracic Surgery, Tampere University, Tampere, FIN.
Trina ChenDepartment of Cardiothoracic Surgery, Tampere University, Tampere, FIN.
Ivana KholovaDepartment of Pathology, Fimlab Laboratories, Tampere University Hospital and Tampere University, Tampere, FIN.
Otso ArponenDepartment of Radiology, Tampere University Hospital and Tampere University, Tampere, FIN.
Petteri KauhanenDepartment of Clinical Radiology, Kuopio University Hospital, Clinical Imaging Center, Kuopio, FIN.
Aada LattuDepartment of Radiology, Tampere University Hospital and Tampere University, Tampere, FIN.
Timo PaavonenDepartment of Pathology, Fimlab Laboratories, Tampere University Hospital and Tampere University, Tampere, FIN.
Ari MennanderDepartment of Cardiothoracic Surgery, Tampere University, Tampere, FIN.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background Ascending aortic dilatation is associated with increased susceptibility to aortic events. Chronic obstructive pulmonary disease (COPD) may add to tissue degeneration and inflammation associated with the risk of increased aortic dilatation. We studied the characteristics and aortic wall degeneration of patients with COPD during ascending aortic dilatation. Methodology We enrolled 35 consecutive patients who underwent elective surgery for ascending aortic dilatation between February 2016 and November 2016. The patients were grouped according to the presence of COPD. The aortic diameters were measured for the aortic valve annulus, aortic root, sinotubular junction, ascending aorta, aortic arch, and descending aorta. An extensive analysis of ascending aortic wall histopathology was performed.  Results The patients with chronic obstructive pulmonary disease (COPD) (n=7) all had aortic valve regurgitation, while the aortic wall had more mucoid extracellular matrix accumulation, medial degeneration, elastic fiber fragmentation and loss, and adventitial fibrosis than those without COPD (5.7±1.1 vs. 4.3±1.0 point score units (PSU),

Indexed as

aortic dilatationaortic surgeryascending aortic degenerationchronic obstructive pulmonary diseasehistology

Identifiers

PMID40951207
PMCPMC12430470

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.