Evidence map›Paper›PMID 40951154›Full record

ReviewCureus2025

Optimizing Postoperative Recovery in Colorectal Surgery: A Systematic Review on the Efficacy of Enhanced Recovery After Surgery (ERAS) Protocols.

Mohey Aldien Ahmed Elamin Elnour, Radwan Alsayed Radwan Ahmed, Ahmed Elkhalifa, Mohamed Eissa Elrayah Omran, Mohamed Ibrahim Osman Hamd, Rouida Elfadil Mohamed Ahmed Aboagla

Abstract readReview
In one paragraph

Review in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Mohey Aldien Ahmed Elamin ElnourNeurosurgery, University Hospitals Coventry and Warwickshire National Health Service (NHS) Trust, Coventry, GBR.
Radwan Alsayed Radwan AhmedGeneral Surgery, Najran Armed Forces Hospital, Ministry of Defense Health Services, Najran, SAU.
Ahmed ElkhalifaGeneral/Colorectal Surgery, Royal Oldham Hospital, Oldham, GBR.
Mohamed Eissa Elrayah OmranSurgery, Dallah Hospital, Riyadh, SAU.
Mohamed Ibrahim Osman HamdGeneral Surgery, Almoweh General Hospital, Taif, SAU.
Rouida Elfadil Mohamed Ahmed AboaglaPediatric Surgery, Ain Shams University Specialized Hospital, Cairo, EGY.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Colorectal surgery carries substantial risks of postoperative morbidity, extended hospital stays, and increased healthcare costs. While the overall benefits of enhanced recovery after surgery (ERAS) protocols are well established, recent studies have expanded their scope to include immunological outcomes, telemedicine integration, and patient-centered recovery metrics. This systematic review synthesizes the latest evidence from randomized controlled trials (RCTs) evaluating ERAS protocols in colorectal surgery, with particular attention to these emerging dimensions. A comprehensive search of PubMed, Scopus, Web of Science, Embase, and ClinicalTrials up to July 2025 identified 10 eligible RCTs from 414 screened records. Risk of bias was assessed using the Cochrane RoB 2 tool. Narrative synthesis was performed due to heterogeneity in ERAS components and outcome definitions. Consistent with prior literature, ERAS accelerated the return of bowel function, reduced the length of hospital stay, and lowered complication rates. Notably, recent trials demonstrated immunological benefits, including reductions in inflammatory markers (IL-6, CRP [C-reactive protein]) and preservation of immune function. Telemedicine-enhanced ERAS pathways, such as remote postoperative monitoring, further shortened recovery times while maintaining high patient satisfaction. Patient-centered outcomes, including functional independence, quality of life, and readiness for home discharge, were significantly improved. Most studies exhibited low risk of bias, although variability in ERAS implementation and reporting persisted. These findings confirm that contemporary ERAS protocols not only optimize physiological recovery but also address immune resilience, leverage digital health tools, and prioritize patient experience. Future research should standardize implementation and assess the long-term effects of these innovations.

Indexed as

colorectal surgeryenhanced recovery after surgeryeraslength of staymultimodal carepostoperative recovery

Identifiers

PMID40951154
PMCPMC12433266

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.