Evidence map›Paper›PMID 40951133›Full record

ArticleCureus2025

Severe Methemoglobinemia Following Alkyl Nitrite Ingestion: A Case Report.

Zane Kalik, Rabiu Momoh

Abstract readCase Reports
In one paragraph

Article in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Zane KalikInternal Medicine, Medway Maritime Hospital, Kent, GBR.
Rabiu MomohCritical Care, Medway Maritime Hospital, Kent, GBR.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We report a case of a 40-year-old male who presented to the emergency department with central cyanosis, altered mental status, and hypoxia that was refractory to supplemental oxygen following ingestion of an alkyl nitrite product called "Liquid Gold". Arterial blood gas and co-oximetry confirmed a diagnosis of severe methemoglobinemia with a methemoglobin (MetHb) level in excess of 30%. The patient was treated with intravenous methylene blue and responded quickly both clinically and biochemically. This case further highlights the need to consider the dangers of recreational nitrite toxicity, the pitfalls of standard pulse oximetry in the setting of dyshemoglobinemia, and the value of prompt antidote therapy when faced with toxicological cases.

Indexed as

acquired methaemoglobinemiaalkyl nitriteco-oximetryemergencieshaemoglobinmethaemoglobinemiaoverdosesaturationssubstance abusetoxicology

Identifiers

PMID40951133
PMCPMC12425463

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.