ArticleFrontiers in medicine2025
Assessment of renal allograft function using amide proton transfer imaging.
Article in Frontiers in medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Objective: This study aimed to investigate the ability of amide proton transfer (APT) imaging to assess the function of transplanted kidneys. Methods: Between October 2023 and July 2024, a total of 44 renal allograft recipients were recruited prospectively, who underwent renal APT imaging with a 3.0 T system 2-3 weeks after transplantation. Recipients were divided into two groups according to the estimated glomerular filtration rate (eGFR): group A, eGFR < 60 mL/min/1.73 m Results: Two physicians calculated APT values independently and with good agreement, as indicated by an intraclass correlation coefficient > 0.75. The renal cortical and medullary APT values in group A (2.61% ± 0.51% and 2.11% ± 0.37%, respectively) were significantly higher than those in group B (1.77% ± 0.13% and 1.79% ± 0.29%, respectively) ( Conclusion: APT imaging is a promising technique for non-invasive functional assessment of renal allografts.
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