Evidence map›Paper›PMID 40950915›Full record

ArticleJournal of thoracic disease2025

Aging population of tracheal, bronchus, and lung cancer: global, regional, and national burden-insights from the Global Burden of Disease Study 2021.

Yuan Liu, Jinxin Zheng, Yi Zhang, Tao Pan, Yuming Wang, Qi Liu, Ziang Wang, Qining He, Yunhai Yang, Hui Zhang and 3 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of thoracic disease, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Yuan Liu *Shanghai Lung Cancer Center, Shanghai Chest Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Jinxin Zheng *School of Global Health, Chinese Center for Tropical Diseases Research, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Yi Zhang *Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Tao PanShanghai Lung Cancer Center, Shanghai Chest Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Yuming WangShanghai Lung Cancer Center, Shanghai Chest Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Qi LiuDepartment of Thoracic Surgery, The Affiliated Cancer Hospital of Zhengzhou University & Henan Cancer Hospital, Zhengzhou, China.
Ziang WangShanghai Lung Cancer Center, Shanghai Chest Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Qining HeShanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Yunhai YangShanghai Lung Cancer Center, Shanghai Chest Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Hui ZhangShanghai Lung Cancer Center, Shanghai Chest Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Chan Siang KanDepartment of Cardiothoracic Surgery, Hospital Sultan Idris Shah, Ministry of Health, Serdang, Malaysia.ORCID https://orcid.org/0000-0003-1601-5023
Ruijun LiuShanghai Lung Cancer Center, Shanghai Chest Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Liwei SongShanghai Lung Cancer Center, Shanghai Chest Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Tracheal, bronchus, and lung (TBL) cancer is the leading cause of cancer-related deaths globally and accounts for the highest incidence among all cancers. We used the Global Burden of Disease (GBD) data from 1990 to 2021 to analyze the burden of TBL cancer by age, sex, and socio-demographic index (SDI) to provide new insights. Methods: We utilized GBD 2021 methodologies to calculate the percentage change (PC) in TBL cancer age-standardized incidence rate (ASIR), age-standardized mortality rate (ASMR), and disability-adjusted life-years (DALYs). Age-period-cohort models predicted TBL cancer incidence and mortality trends for 2035. The elderly population (EP) was stratified as <70 Results: In 2021, TBL cancer accounted for 2.28 million [95% uncertainty interval (UI): 2.06-2.51] new cases, 2.04 million (95% UI: 1.88-2.19) deaths, and 45.9 million (95% UI: 42.3-49.3) DALYs. ASIR in males declined significantly (PC =-11.2%, 95% UI: -21.7% to -0.4%), while it slightly increased in females (PC =0.9%, 95% UI: -8.3% to 11.4%). Non-elderly (<70 years) and elderly (≥70 years) populations each contributed around 1.1 million cases, but ASIR was markedly higher in the elderly (225.78 Conclusions: The burden of TBL cancer is projected to rise with population aging, particularly among women. The increasing ASIR and ASMR in females warrant urgent investigation of risk factors and targeted preventive measures to curb this trend.

Indexed as

agingglobalincidenceLung cancermortality

Identifiers

PMID40950915
PMCPMC12433117

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.