ArticleJournal of thoracic disease2025
The diagnostic value of CD101 in smear-negative pulmonary tuberculosis.
Article in Journal of thoracic disease, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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7 authors.
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Abstract
Background: Unlike smear-positive tuberculosis (TB) which is more easily diagnosed due to the presence of Methods: Sixty-three newly treated patients with TB and negative smear results diagnosis by clinicians were included as the SN-TB group, while 59 healthy individuals [healthy control (HC)] were included as the control group. The expression of CD101 in PBMCs of the two groups was detected via real-time quantitative polymerase chain reaction (RT-qPCR). The expression of CD101 on T cells and NK cells, as well as the expression of T helper (Th) 1/2/17-related cytokines was detected by flow cytometry. Spearman analysis was used to analyze the correlation between CD101 expression, cytokines and clinical indicators in patients with SN-TB. Receiver operating characteristic (ROC) curve analysis was used to analyze the sensitivity and specificity of CD101 alone or in combination with other cytokines in diagnosing SN-TB. Results: Compared with the control group, the experimental group showed high CD101 expression in PBMCs and CD4 Conclusions: The expression of CD101 on CD4
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