ArticleJournal of thoracic disease2025
Effects of nutritional support during neoadjuvant therapy on perioperative outcome in esophageal cancer: a real-world cohort study.
Article in Journal of thoracic disease, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
1 citing paper in PubMed.
- Efficacy of double-point jejunostomy in laparoscopic surgery for esophageal cancer: a comparative study.Journal of thoracic disease · 2026Article
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Authors and funding
13 authors.
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Abstract
Background: While postoperative nutritional support for esophageal cancer is well-documented, the impact of nutritional intervention during neoadjuvant therapy remains understudied. This study investigates the role of nutritional support during neoadjuvant therapy in improving perioperative outcomes for esophageal cancer patients. Methods: A retrospective analysis of 454 esophagectomy patients following neoadjuvant therapy was conducted. Patients were categorized into a nutrition effective group (weight maintenance or gain, n=304) and a control group (weight loss, n=150) according to their weight change after nutritional intervention. Preoperative nutritional status, therapy completion, adverse reactions, postoperative pathological outcomes, and complications were compared between groups. Results: Compared to the control group, the nutrition effective group demonstrated (I) improved nutritional status during neoadjuvant therapy with higher body mass index (BMI) changes (0.85±0.88 Conclusions: Nasogastric tube feeding plays a pivotal role in effective nutritional support during neoadjuvant therapy. Effective nutritional intervention not only improves preoperative nutritional status and enhances neoadjuvant therapy completion but also mitigates grade 3 or higher adverse events and reduces the incidence of anastomotic leakage. Additionally, it may potentially contribute to improved postoperative pathological remission.
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