ReviewFrontiers in microbiology2025
Insect-specific viruses: transmission dynamics and biological control strategies against arboviruses.
Review in Frontiers in microbiology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
3 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Effects of insect-specific viruses on transmission, infection, and replication of arboviruses in co-infected mosquitoes: a systematic review.Parasites & vectors · 2026Pooled it
- Article
- RNA metagenomic profiling of mosquito viromes associated with Vector-Borne diseases in Quebec, Canada.PloS one · 2026Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Mosquitoes are known to vector arthropod-borne viruses (arboviruses) that pose a global public health issue in the form of mosquito-borne viral diseases such as chikungunya fever, dengue fever, Japanese encephalitis, yellow fever, and Zika. Besides, mosquitoes may also carry insect-specific viruses (ISVs), which are evolutionarily alike arboviruses yet do not infect vertebrates. These ISVs have been shown to affect the ability of mosquitoes to transmit arboviruses, as well as potentially inhibit arbovirus infections in vertebrate hosts. Yet, ISVs still constitute a relatively new and little-researched area where further studies may yield new knowledge regarding their distribution, their future importance in the control of mosquito-borne viral disease and potential role in biological control of mosquitoes. This review provides insights into ISV classification, transmission, and biology, as well as historical and future aspects. It mainly focuses on the characterization of the transmission dynamics of ISVs to highlight the various potential arboviral pathogen transmission blocking mechanisms along with evolution and host tropism. The review also provides additional information on the potential use of ISVs as a method of biological control in comparison to other proposed methods as well as delving into current research into arbovirus-based vaccines and antiviral drug development.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.