Evidence map›Paper›PMID 40950582›Full record

SynthesisFrontiers in microbiology2025

Unraveling the HIV-malaria interactions: a bibliometric analysis of global research trends and emerging insights.

Huize Zhang, Guoren Chen, Ping Ma, Yu Lai

Abstract readSystematic Review
In one paragraph

Synthesis in Frontiers in microbiology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Huize ZhangSchool of Basic Medicine, Chengdu University of Traditional Chinese Medicine, Chengdu, China.
Guoren ChenSchool of Basic Medicine, Chengdu University of Traditional Chinese Medicine, Chengdu, China.
Ping MaSchool of Basic Medicine, Chengdu University of Traditional Chinese Medicine, Chengdu, China.
Yu LaiSchool of Basic Medicine, Chengdu University of Traditional Chinese Medicine, Chengdu, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: The co-infection of human immunodeficiency virus (HIV) and malaria has emerged as an urgent public health challenge in tropical areas where the two diseases geographically converge, stimulating extensive biomedical investigations into their pathobiological interactions. This study aims to elucidate the current status and research trends regarding the interactions between HIV and malaria through bibliometric and visualized analysis. Methods: Research on the interactions between HIV and malaria was collected from the Web of Science Core Collection. Bibliometric analysis and knowledge graph visualization were performed on 4,717 articles published between 1995 and 2024, using CiteSpace software. Results: The results demonstrate a fluctuating upward pattern in the number of publications related to HIV and malaria interactions. According to the cooperative network visualization analysis, the United States, the University of London, and Grant Dorsey possess the greatest publication counts among all countries, institutions, and authors, respectively. The keyword and cocited reference analysis distinguish the primary research hotspots and frontiers as the epidemiological study of different populations in the African region, pathogenic mechanisms underlying HIV-malaria co-infection, strategies for the prevention and treatment of HIV and malaria co-infection, interactions between antimalarial and antiretroviral drugs, and malaria vaccine responses in HIV-infected individuals. Conclusion: This bibliometric investigation outlines the research hotspots, frontiers, and trends regarding the interactions between HIV and malaria. Future research should delineate pharmacokinetic and pharmacodynamic interactions between antimalarial and antiretroviral drugs to enhance clinical efficacy and medication safety and develop effective malaria vaccines that benefit HIV-positive populations in endemic areas.

Indexed as

bibliometric analysisco-infectionHIVinteractionsmalariavisualized analysis

Identifiers

PMID40950582
PMCPMC12426043

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.