Evidence map›Paper›PMID 40950578›Full record

ArticleFrontiers in microbiology2025

Species-level taxonomic characterization of gut microbiota in HIV-infected individuals.

Jiali Chen, Tingting Yuan, Han Zheng, Lianfeng Li, Ji Pu, Shan Lu, Yamin Sun, Wenchao Lin, Jun Chen, Mingquan Guo and 4 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in microbiology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Jiali Chen *School of Medicine, Research Institute of Public Health, Nankai University, Tianjin, China.
Tingting Yuan *School of Medicine, Research Institute of Public Health, Nankai University, Tianjin, China.
Han ZhengNational Key Laboratory of Intelligent Tracking and Forecasting for Infectious Diseases, National Institute for Communicable Disease Control and Prevention, Chinese Center for Disease Control and Prevention, Beijing, China.
Lianfeng LiInstitute of EcoHealth, School of Public Health, Cheeloo College of Medicine, Shandong University, Jinan, China.
Ji PuNational Key Laboratory of Intelligent Tracking and Forecasting for Infectious Diseases, National Institute for Communicable Disease Control and Prevention, Chinese Center for Disease Control and Prevention, Beijing, China.
Shan LuNational Key Laboratory of Intelligent Tracking and Forecasting for Infectious Diseases, National Institute for Communicable Disease Control and Prevention, Chinese Center for Disease Control and Prevention, Beijing, China.
Yamin SunNational Key Laboratory of Intelligent Tracking and Forecasting for Infectious Diseases, Beijing Ditan Hospital, Capital Medical University, Beijing, China.
Wenchao LinUniteomics Tianjin Biotechnology Co., Ltd., Tianjin, China.
Jun ChenShanghai Public Health Clinical Center, Fudan University, Shanghai, China.
Mingquan GuoShanghai Public Health Clinical Center, Fudan University, Shanghai, China.
Yubin LuShanghai Public Health Clinical Center, Fudan University, Shanghai, China.
Zhaoqin ZhuShanghai Public Health Clinical Center, Fudan University, Shanghai, China.
Jing YangNational Key Laboratory of Intelligent Tracking and Forecasting for Infectious Diseases, National Institute for Communicable Disease Control and Prevention, Chinese Center for Disease Control and Prevention, Beijing, China.
Jianguo XuSchool of Medicine, Research Institute of Public Health, Nankai University, Tianjin, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Most current HIV gut microbiota studies, based on 16S rRNA gene sequencing, are limited to the genus level. Since different genera encompass several to hundreds of species, in this study, we performed research at the species level based on the HGMAD database. This cross-sectional study investigated differences in gut microbiota between healthy control (HC) subjects and people with HIV (PWH) at the species level, characterized the specific enterotype and the correlation between gut microbiota patterns and immune status in PWH. We recruited 114 individuals in the PWH group and 58 individuals in the HC group, from whom fecal samples were collected for 16S rRNA gene sequencing of the V3-V4 region. Significant differences in α diversity and β diversity (

Indexed as

enterotypegut microbiotaHIVimmune statusspecies level

Identifiers

PMID40950578
PMCPMC12427029

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.