ArticleJournal of clinical and experimental dentistry2025
Strontium-Zinc conversion coating on magnesium plates for resorbable tack screws in guided bone regeneration: Characterization and biocompatibility evaluation.
Article in Journal of clinical and experimental dentistry, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Background: Guided bone regeneration (GBR) requires resorbable implants that balance corrosion resistance and biocompatibility. Magnesium (Mg) is a promising candidate, but its rapid degradation necessitates protective coatings. This study develops and characterizes a strontium-zinc (Sr-Zn) conversion coating on Mg plates for resorbable tack screws, evaluating its corrosion resistance, surface properties, and biocompatibility. Material and Methods: Mg plates (20×15×2 mm) were etched with HCl, coated with Sr-Zn via immersion (30 min, pH 3-5), and characterized using SEM, EDX, and FTIR. Corrosion resistance was assessed via potentiodynamic polarization in simulated body fluid (SBF). Biocompatibility was evaluated using MG63 osteoblast cultures, with statistical comparison (Student's t-test, Results: SEM revealed a dense, fibrous coating with interconnected pores, enhancing cell adhesion. EDX confirmed Zn (46.6 wt%) and Sr (3.7 wt%) incorporation. FTIR identified hydroxyl/carbonyl groups and metal-oxygen bonds. The coating improved corrosion resistance compared to bare Mg plates. In vitro cell culture assays demonstrated that Sr-Zn conversion-coated Mg plates (Group A) showed comparable cell viability to bare Mg plates (Group B) at all tested time points. Peak cell viability was recorded at 24 hours, with Group A achieving 92.66% and Group B reaching 91% ( Conclusions: The Sr-Zn coating improved Mg's corrosion resistance while maintaining osteoblast viability, supporting its potential for resorbable GBR tack screws.
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