Evidence map›Paper›PMID 40950484›Full record

ArticlemedRxiv : the preprint server for health sciences2025

Appendix300: A multi-institutional laparoscopic appendectomy video dataset for computational modeling tasks.

Fiona R Kolbinger, Max Kirchner, Kevin Pfeiffer, Sebastian Bodenstedt, Alexander C Jenke, Julia Barthel, Matthias Carstens, Karolin Dehlke, Sophia Dietz, Sotirios Emmanouilidis and 18 more

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In one paragraph

Article in medRxiv : the preprint server for health sciences, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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3 · Its place in the literature

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0 citing papers in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

28 authors.

Fiona R KolbingerDepartment of Visceral, Thoracic and Vascular Surgery, University Hospital and Faculty of Medicine Carl Gustav Carus, TUD Dresden University of Technology, Dresden, Germany.ORCID 0000-0003-2265-4809
Max KirchnerDepartment of Translational Surgical Oncology, National Center for Tumor Diseases (NCT), NCT/UCC Dresden, a partnership between DKFZ, Faculty of Medicine and University Hospital Carl Gustav Carus, TUD Dresden University of Technology, and Helmholtz-Zentrum Dresden-Rossendorf (HZDR), Germany.
Kevin PfeifferElse Kroener Fresenius Center for Digital Health, Faculty of Medicine and University Hospital Carl Gustav Carus, TUD Dresden University of Technology, Dresden, Germany.
Sebastian BodenstedtDepartment of Translational Surgical Oncology, National Center for Tumor Diseases (NCT), NCT/UCC Dresden, a partnership between DKFZ, Faculty of Medicine and University Hospital Carl Gustav Carus, TUD Dresden University of Technology, and Helmholtz-Zentrum Dresden-Rossendorf (HZDR), Germany.ORCID 0000-0002-2203-9729
Alexander C JenkeDepartment of Translational Surgical Oncology, National Center for Tumor Diseases (NCT), NCT/UCC Dresden, a partnership between DKFZ, Faculty of Medicine and University Hospital Carl Gustav Carus, TUD Dresden University of Technology, and Helmholtz-Zentrum Dresden-Rossendorf (HZDR), Germany.ORCID 0000-0002-4675-417X
Julia BarthelDepartment of Visceral, Thoracic and Vascular Surgery, University Hospital and Faculty of Medicine Carl Gustav Carus, TUD Dresden University of Technology, Dresden, Germany.
Matthias CarstensDepartment of Visceral, Thoracic and Vascular Surgery, University Hospital and Faculty of Medicine Carl Gustav Carus, TUD Dresden University of Technology, Dresden, Germany.
Karolin DehlkeDepartment of Visceral, Thoracic and Vascular Surgery, University Hospital and Faculty of Medicine Carl Gustav Carus, TUD Dresden University of Technology, Dresden, Germany.
Sophia DietzDepartment of Visceral, Thoracic and Vascular Surgery, University Hospital and Faculty of Medicine Carl Gustav Carus, TUD Dresden University of Technology, Dresden, Germany.
Sotirios EmmanouilidisDepartment of General, Visceral and Thoracic Surgery, St. Elisabethen-Klinikum Ravensburg, Ravensburg, Germany.
Guido FitzeDepartment of Pediatric Surgery, University Hospital and Faculty of Medicine Carl Gustav Carus, TUD Dresden University of Technology, Dresden, Germany.
Martin FreitagKrankenhaus St. Joseph-Stift Dresden GmbH, Dresden, Germany.
Fabian HolderriedDepartment of General, Visceral and Thoracic Surgery, St. Elisabethen-Klinikum Ravensburg, Ravensburg, Germany.
Thorsten JacobiDiakonissenkrankenhaus Dresden, Dresden, Germany.
Weam KanjoKrankenhaus St. Joseph-Stift Dresden GmbH, Dresden, Germany.
Linda LeitermannDepartment of General and Visceral Surgery, Dresden-Friedrichstadt General Hospital, Dresden, Germany.
Sören Torge MeesDepartment of General and Visceral Surgery, Dresden-Friedrichstadt General Hospital, Dresden, Germany.
Steffen PistoriusDepartment of Visceral, Thoracic and Vascular Surgery, University Hospital and Faculty of Medicine Carl Gustav Carus, TUD Dresden University of Technology, Dresden, Germany.
Conrad PrudloDepartment of Pediatric Surgery, University Hospital and Faculty of Medicine Carl Gustav Carus, TUD Dresden University of Technology, Dresden, Germany.
Astrid SeiberthDepartment of General and Visceral Surgery, Dresden-Friedrichstadt General Hospital, Dresden, Germany.
Jurek SchultzDepartment of Pediatric Surgery, University Hospital and Faculty of Medicine Carl Gustav Carus, TUD Dresden University of Technology, Dresden, Germany.ORCID 0000-0001-5638-8663
Karolin ThielDepartment of General, Visceral and Thoracic Surgery, St. Elisabethen-Klinikum Ravensburg, Ravensburg, Germany.
Daniel ZiehnDiakonissenkrankenhaus Dresden, Dresden, Germany.
Stefanie SpeidelDepartment of Translational Surgical Oncology, National Center for Tumor Diseases (NCT), NCT/UCC Dresden, a partnership between DKFZ, Faculty of Medicine and University Hospital Carl Gustav Carus, TUD Dresden University of Technology, and Helmholtz-Zentrum Dresden-Rossendorf (HZDR), Germany.ORCID 0000-0002-4590-1908
Jürgen WeitzDepartment of Visceral, Thoracic and Vascular Surgery, University Hospital and Faculty of Medicine Carl Gustav Carus, TUD Dresden University of Technology, Dresden, Germany.
Jakob Nikolas KatherElse Kroener Fresenius Center for Digital Health, Faculty of Medicine and University Hospital Carl Gustav Carus, TUD Dresden University of Technology, Dresden, Germany.ORCID 0000-0002-3730-5348
Marius DistlerDepartment of Visceral, Thoracic and Vascular Surgery, University Hospital and Faculty of Medicine Carl Gustav Carus, TUD Dresden University of Technology, Dresden, Germany.ORCID 0000-0002-3164-5755
Oliver Lester SaldanhaElse Kroener Fresenius Center for Digital Health, Faculty of Medicine and University Hospital Carl Gustav Carus, TUD Dresden University of Technology, Dresden, Germany.ORCID 0000-0002-3594-7590

Funding

Indiana Clinical and Translational Sciences InstituteUM1TR004402 · NCATS · INDIANA UNIVERSITY INDIANAPOLIS · PI Sharon M Moe, Sarah Elizabeth Wiehe · 2023 to 2026
$21.6M
Integration of epidemiology, pathology, immunology and outcomes in colorectal cancerR01CA263318 · NCI · BECKMAN RESEARCH INSTITUTE/CITY OF HOPE · PI STEPHEN B GRUBER · 2022 to 2026
$3.4M
NCATS NIH HHS UM1 TR004402NCI NIH HHS R01 CA263318
6 · The paper itself

Abstract

Background: The limited availability of diverse and representative training data poses a critical barrier to the development of clinically relevant computational tools for intraoperative surgical decision support. Surgical procedures are not routinely recorded, and annotation requires domain expertise, resulting in a scarcity of open-access surgical video datasets with high-quality annotations. Existing datasets are typically limited to single institutions and specific procedures, such as cholecystectomy, and rarely comprise patient-level metadata like demographic characteristics, disease history, or laboratory parameters. Methods: The Appendix300 dataset comprises 330 laparoscopic surgery recordings, including 325 full-length laparoscopic appendectomies and 5 control recordings from non-appendectomy procedures in pediatric and adult patients treated at five German centers. The dataset includes patient-level clinical metadata (demographics, medical history, clinical symptoms, laboratory parameters, and histopathological findings), as well as standardized expert annotations of the laparoscopic grade of appendicitis. Results: Appendix300 currently represents the largest publicly available collection of surgical video data with patient metadata and the first curated dataset of laparoscopic appendectomies. It enables novel validation tasks for computer vision in surgery, including the classification of appendicitis severity and the detection of appendiceal perforation. Technical validation of the laparoscopic appendicitis grade annotations showed substantial interrater agreement (weighted Cohen's κ = 0.615). Conclusion: The Appendix300 dataset expands the scope of surgical data science by integrating video data with clinical and pathological metadata across institutions. It enables new and clinically relevant patient-level validation tasks for computer vision in laparoscopic surgery and facilitates decentralized learning approaches, overall enhancing the breadth and translational relevance of AI-based surgical video analysis.

Identifiers

PMID40950484
PMCPMC12424895

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