Evidence map›Paper›PMID 40950466›Full record

ArticlemedRxiv : the preprint server for health sciences2025

Multi-Omics Validation of Myelin Water Fraction as a Myelin-Specific MRI Biomarker.

Jonghyun Bae, Cassandra M Joynes, Zhaoyuan Gong, Michael R Duggan, Keenan A Walker, Mustapha Bouhrara

Abstract readPreprint
In one paragraph

Article in medRxiv : the preprint server for health sciences, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

6 authors.

Jonghyun BaeNational Institute on Aging, Baltimore, 21224 MD, USA.ORCID 0000-0002-3987-6603
Cassandra M JoynesNational Institute on Aging, Baltimore, 21224 MD, USA.
Zhaoyuan GongNational Institute on Aging, Baltimore, 21224 MD, USA.
Michael R DugganNational Institute on Aging, Baltimore, 21224 MD, USA.
Keenan A WalkerNational Institute on Aging, Baltimore, 21224 MD, USA.ORCID 0000-0002-5989-9853
Mustapha BouhraraNational Institute on Aging, Baltimore, 21224 MD, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The myelin sheath is critical for efficient neural signaling and central nervous system function, yet noninvasive methods to quantify myelin content

Identifiers

PMID40950466
PMCPMC12425030

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.