Evidence map›Paper›PMID 40950411›Full record

ArticleFrontiers in cell and developmental biology2025

High-glucose diets differentially modulate phosphatidylcholine metabolism and fecundity in

Chao-Wen Wang, Phebe Chiu, Sophia Monsalve, Ricardo Roure, Xiaofei Bai, Jia-Jin Law, Yu-Ching Wu, Yet-Ran Chen, You-Liang Cheng, Rey-Huei Chen and 1 more

Abstract read
In one paragraph

Article in Frontiers in cell and developmental biology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. AbioRxiv : the preprint server for biology · 2026
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Chao-Wen WangDepartment of Life Sciences, National Cheng Kung University, Tainan, Taiwan.
Phebe ChiuInstitute of Plant and Microbial Biology, Academia Sinica, Taipei, Taiwan.
Sophia MonsalveDepartment of Biology and Genetics Institute, University of Florida, Gainesville, FL, United States.
Ricardo RoureDepartment of Biology and Genetics Institute, University of Florida, Gainesville, FL, United States.
Xiaofei BaiDepartment of Biology and Genetics Institute, University of Florida, Gainesville, FL, United States.
Jia-Jin LawInstitute of Plant and Microbial Biology, Academia Sinica, Taipei, Taiwan.
Yu-Ching WuInstitute of Plant and Microbial Biology, Academia Sinica, Taipei, Taiwan.
Yet-Ran ChenInstitute of Agricultural Biotechnology Research Center, Academia Sinica, Taipei, Taiwan.
You-Liang ChengInstitute of Molecular Biology, Academia Sinica, Taipei, Taiwan.
Rey-Huei ChenInstitute of Molecular Biology, Academia Sinica, Taipei, Taiwan.
Yi-Chun WuInstitute of Molecular and Cellular Biology, National Taiwan University, Taipei, Taiwan.

Funding

Modeling PIEZO associated diseases in Caenorhabditis elegans: from genetics to mechanismR00GM145224 · NIGMS · UNIVERSITY OF FLORIDA · PI BAI, XIAOFEI · 2023 to 2025
$727k
NIGMS NIH HHS R00 GM145224
6 · The paper itself

Abstract

Background: Methods: A differential high-glucose diet paradigm was established using Results: Conclusion: We demonstrate that dietary cues under high-glucose conditions modulate a genetic network linking lipid homeostasis and signaling pathways, ultimately determining fecundity outcomes in

Indexed as

cholinedietglucosemethionineomicsphosphatidylcholinetriacylglycerolvitamin B12

Identifiers

PMID40950411
PMCPMC12425989

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.