ArticleAmerican journal of translational research2025
Minimally invasive total hip arthroplasty versus minimally invasive hemiarthroplasty for geriatric femoral neck fractures: efficacy and impact on inflammatory and stress markers.
Article in American journal of translational research, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
1 citing paper in PubMed.
- Total hip replacement versus bipolar femoral head replacement for femoral neck fractures in the elderly: effect on surgical indices, hip function, and postoperative complications.American journal of translational research · 2026Article
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7 authors.
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Abstract
objectiveTo compare the clinical efficacy, inflammatory responses, and surgical stress between minimally invasive total hip arthroplasty (MIS-THA) and minimally invasive hemiarthroplasty (MIS-HA) in the treatment of femoral neck fractures (FNFs) in elderly patients.
methodsFrom December 2018 to December 2021, 98 elderly patients with FNFs were enrolled, with 50 undergoing MIS-THA (observation group) and 48 undergoing MIS-HA (reference group). The clinical efficacy, surgery-related parameters (including intraoperative blood loss, postoperative drainage volume, and operation time), postoperative recovery (hip joint recovery time and hospitalization), and complication rates were compared between the two groups. Interleukin-6 (IL-6), C-reactive protein (CRP), Harris Hip Score, and Visual Analog Scale (VAS) scores were assessed preoperatively and postoperatively. Cortisol (Cor) and malondialdehyde (MDA) levels were measured at four time points: preoperatively (T0), immediately postoperatively (T1), and at 24 hours (T2) and 72 hours (T3) post-surgery. Additionally, efficacy comparisons were conducted across different age groups and fracture types.
resultsThe observation group demonstrated significantly higher treatment efficacy, shorter hip recovery time, and better functional outcomes (as evidenced by higher Harris and lower VAS scores) compared to the reference group. MIS-THA was associated with longer operative time, greater blood loss, and increased drainage volume (P<0.05), while hospitalization time and complication rates were comparable between groups (P>0.05). Postoperative IL-6 and CRP levels were elevated in both groups, but remained lower in the observation group (P<0.05). Stress markers (Cor and MDA) peaked at T2 and declined thereafter, with milder fluctuations observed in the observation group (P<0.05). The total effectiveness rate didn't differ significantly between the two groups across different age groups and fracture types.
conclusionMIS-THA provides superior efficacy, faster functional recovery, and more pronounced pain relief, along with a milder inflammatory and stress response, compared to MIS-HA in elderly patients with FNFs. Despite longer operation time, greater intraoperative blood loss, and higher postoperative drainage, MIS-THA and MIS-HA exhibit similar safety profiles, as evidenced by comparable hospitalization durations and complication rates.
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