ArticleAmerican journal of translational research2025
Prognostic factors in retroperitoneal liposarcoma after R0 resection: a study of age, histologic type, tumor stage, and differentiation grade.
Article in American journal of translational research, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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Who cites it
1 citing paper in PubMed.
- Retroperitoneal dedifferentiated liposarcoma with colon infiltration: a case report and literature review.Frontiers in oncology · 2025Article
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Authors and funding
6 authors.
Funding
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Abstract
objectiveThis study aimed to identify prognostic factors affecting progression-free survival (PFS) in patients with retroperitoneal liposarcoma (RPLS) after R0 resection.
methodsA retrospective analysis was conducted on 183 RPLS patients who underwent R0 resection, evaluating general information, clinicopathological data, laboratory parameters, and follow-up outcomes. Based on follow-up outcomes, patients were categorized into progression-free survival (PFS) group (PFS, n=121) and disease progression group (DP, n=62). The general information, clinicopathological data, and laboratory parameters of the two groups were systematically compared, with statistically significant factors subsequently incorporated into the Cox multivariate regression analysis. Significant prognostic factors identified through Cox analysis were further evaluated using Kaplan-Meier (K-M) survival analysis, serving as the foundation for constructing the predictive model. The model's performance was rigorously assessed for 1-year, 3-year, and overall PFS prediction.
resultsMultivariate analysis identified age (
conclusionAdvanced age, DDLPS, PLS, stage III-IV disease, and poor tumor differentiation were identified as independent predictors of shorter PFS in RPLS patients following R0 resection.
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