Evidence map›Paper›PMID 40950298›Full record

ArticleAmerican journal of translational research2025

Clinical advantages of multifocal soft contact lenses in myopia control for adolescents.

Yongmei Cao, Jiabao Liu

Abstract read
In one paragraph

Article in American journal of translational research, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Yongmei CaoDepartment of Pediatric Ophthalmology, Suzhou Lixiang Eye Hospital Suzhou 215000, Jiangsu, China.
Jiabao LiuDepartment of Pediatric Ophthalmology, Suzhou Lixiang Eye Hospital Suzhou 215000, Jiangsu, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo compare the clinical effectiveness of multifocal soft contact lenses (MFSCLs) and orthokeratology (OK) lenses in managing myopia in adolescents.

methodsThis retrospective study enrolled 106 myopic adolescents, divided into two groups: OK (n=50) and MFSCLs (n=56). Refractive error (RE), intraocular pressure (IOP), axial length (AL), and choroidal thickness were measured at baseline (T0), 6-month follow-up (T1), and 12-month follow-up (T2). Additionally, accommodative amplitude, accommodative sensitivity, negative/positive relative accommodation (NRA/PRA), interleukin-6 (IL-6), epidermal growth factor (EGF), psychological status, and quality of life were compared between T0 and T2. Safety during treatment was also assessed.

resultsBoth interventions resulted in a significant increase in RE at T1 and T2 (P<0.05), with no significant differences between groups (P>0.05). IOP, AL, and choroidal thickness remained stable (all P>0.05). At T2, the MFSCLs group showed significant improvements in accommodative amplitude, accommodative sensitivity, and NRA (all P<0.05), along with a reduction in PRA (P<0.05), although no significant inter-group differences were observed (P>0.05). Furthermore, the MFSCLs group exhibited significantly lower IL-6 levels, higher EGF, and fewer adverse reactions (all P<0.05). Psychological status and quality of life improvements were significantly greater in the MFSCLs group (P<0.05).

conclusionMFSCLs and OK lenses demonstrate comparable myopia control effects. However, MFSCLs offer additional benefits in reducing inflammation, enhancing safety, and improving mental health and quality of life.

Indexed as

adolescent myopiaMultifocal soft contact lensesmyopia managementorthokeratology lenses

Identifiers

PMID40950298
PMCPMC12432735

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.