Evidence map›Paper›PMID 40950291›Full record

ArticleAmerican journal of translational research2025

Therapeutic effect of permeable resin and composite resin filling combined with self-etching adhesive in the treatment of dental caries in children.

Chen Ma, Xiaofei Wang, Jin Li

Abstract read
In one paragraph

Article in American journal of translational research, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Chen MaDepartment of Stomatology, Shenzhen Second People's Hospital Shenzhen 518032, Guangdong, China.
Xiaofei WangDepartment of Stomatology, Shenzhen Second People's Hospital Shenzhen 518032, Guangdong, China.
Jin LiDepartment of Stomatology, Shenzhen Second People's Hospital Shenzhen 518032, Guangdong, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo evaluate the clinical effect of permeable resin filling compared with composite resin filling compared with a self-etching adhesive in the treatment of dental caries in children.

methodsA retrospective analysis was conducted on the clinical data of 118 children with dental caries treated at Shenzhen Second People's Hospital from April 2021 to April 2024. According to the treatment plans, patients were divided into two groups: the control group (n = 59), treated with composite resin filling and a self-etching adhesive, and the observation group (n = 59), treated with permeable resin filling. The overall clinical efficacy and adverse reactions were assessed at 3, 6 and 12 months after treatment. In addition, inflammatory markers [Tumor necrosis factor-α (TNF-α), interleukin-6 (IL-6), interleukin-8 (IL-8)], periodontal health indicators [bleeding index (BI), plaque index (PLI), gingival index (GI), probe depth (PD)], restoration quality (marginal adaptation rate and retention rate), tooth sensitivity, treatment cooperation [visual analog scale (VAS) score, Tactile value, Schiff score, Houpt score, Frank1 score] and oral health-related quality of life-based on the Children's Oral Health Impact Profile (COHIP) scale were evaluated before and 3 months after treatment.

resultsAt 3, 6 and 12 months after treatment, the observation group showed significantly higher overall clinical efficacy compared to the control group (P < 0.05). Subgroup analysis revealed that among patients with superficial caries, the observation group achieved a significantly higher response rate (P < 0.05). After treatment, levels of TNF-α, IL-6, IL-8, BI, PLI, GI, PD, VAS, Schiff score, Houpt score, Frank1 score, and COHIP score decreased in both groups, while tactile value increased. Moreover, the observation group exhibited greater improvements across all inflammatory, periodontal, restorative, tooth sensory, behavioral and quality of life metrics compared to the control group (P < 0.05). The incidence of adverse reactions was 5.08% in the observation group and 13.56% in the control group, with no statistically significant difference (P > 0.05).

conclusionPermeable resin filling demonstrates superior permeability, enhanced caries repair outcomes, and favorable safety in the treatment of pediatric dental caries, making it a clinically valuable therapeutic option.

Indexed as

composite resindental cariesPermeable resinself-etching adhesive

Identifiers

PMID40950291
PMCPMC12432702

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.