ArticleAmerican journal of translational research2025
Tricuspid annular dilation and occluder deviation predict worsening of tricuspid regurgitation after transcatheter closure of atrial septal defect with patent foramen ovale.
Article in American journal of translational research, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveTo evaluate the predictive value of echocardiographic findings for postoperative tricuspid regurgitation (TR) worsening after transcatheter atrial septal defect (ASD) with patent foramen ovale (PFO) closure using domestic occluders, and to develop a dynamic risk prediction model to guide clinical decision-making.
methodsThis retrospective cohort study included 109 patients undergoing ASD/PFO closure with occluders (manufactured domestically in China) at a single center (between January 2018 and May 2024). Participants were stratified into an observation group (TR worsening ≥ 1 grade, n = 26) and a control group (stable TR, n = 83). Echocardiographic data - including tricuspid annular diameter, coaptation height, and occluder positional deviation - were assessed preoperatively, immediately postoperatively, and at 1-year follow-up. Univariate and multivariate logistic regression analyses were performed to identify independent predictors. Model performance was evaluated using receiver operating characteristic (ROC) curves.
resultsCompared to controls, the observation group (n = 26) exhibited significantly greater tricuspid annular dilation (mean Δdiameter: 3.2 ± 0.8 mm vs 0.9 ± 0.4 mm; P < 0.001) and occluder positional deviation (4.1 ± 1.2 mm vs 1.8 ± 0.6 mm; P < 0.001). Multivariate analysis identified Δtricuspid annular diameter (OR = 1.32 per 1-mm increase, 95% CI: 1.12-1.56; P < 0.001) and occluder deviation (OR = 2.41 per 1-mm increase, 95% CI: 1.68-3.45; P < 0.001) as independent predictors of TR worsening. The combined predictive model demonstrated superior discrimination (AUC = 0.802, 95% CI: 0.742-0.862; sensitivity = 76.9%, specificity = 81.3%) outperforming their individual application (P < 0.001). Subgroup analysis showed consistent predictive performance across occluder types (P
conclusionDynamic tricuspid annular dilation and occluder malposition erre independent risk factors for postoperative TR progression. The echocardiography-based predictive model enhances risk stratification and may inform intraprocedural adjustments and postoperative surveillance.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.