Evidence map›Paper›PMID 40950216›Full record

ArticlebioRxiv : the preprint server for biology2025

Coronavirus NSP14 Drives Internal m

Ensueño Esmeralda Sáenz Altamirano, Chien-Hsin Huang, Yueh-Lin Tsai, Tiffany J Tzeng, Natália Fagundes Borges Teruel, Isha Pandey, Neelam Oswal, Y Grace Chen, Ching-Wen Chang, Ricardo Rajsbaum and 3 more

Abstract readPreprint
In one paragraph

Article in bioRxiv : the preprint server for biology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

13 authors.

Ensueño Esmeralda Sáenz Altamirano
Chien-Hsin Huang
Yueh-Lin Tsai
Tiffany J Tzeng
Natália Fagundes Borges Teruel
Isha Pandey
Neelam Oswal
Y Grace Chen
Ching-Wen Chang
Ricardo Rajsbaum
Jack Chun-Chieh HsuORCID 0000-0003-4380-8723

Funding

The Role of the Host Ubiquitin System in Promoting SARS-CoV-2 Replication and PathogenesisR01AI166668 · NIAID · UNIVERSITY OF TEXAS MED BR GALVESTON · PI RAJSBAUM, RICARDO · 2021 to 2025
$2.6M
Understanding the Molecular Basis of Translation Inhibition by SARS-CoV-2 NSP14 and its Role in SARS-CoV-2 Immune EvasionK22AI168257 · NIAID · RUTGERS BIOMEDICAL AND HEALTH SCIENCES · PI HSU, CHUN CHIEH · 2023 to 2024
$266k
NIAID NIH HHS K22 AI168257NIAID NIH HHS R01 AI166668
6 · The paper itself

Abstract

SARS-CoV-2, the causative agent of COVID-19, manipulates host gene expression through multiple mechanisms, including disruption of RNA processing. Here, we identify a novel function of the viral nonstructural protein 14 (NSP14) in inducing

Identifiers

PMID40950216
PMCPMC12424731

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.