ArticlebioRxiv : the preprint server for biology2025
Regulatory logic of neuronal identity specification in
Article in bioRxiv : the preprint server for biology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
During neurogenesis, signaling molecules and transcription factors (TFs) pattern neural progenitors across space and time to generate the numerous cell types that constitute neural circuits. In postmitotic neurons, these identities are established and maintained by a class of TFs known as terminal selectors (tsTFs). However, it remains largely unclear how the tsTF combinations are specified, and how they then coordinate the type-specific differentiation programs of each neuron. To investigate these regulatory mechanisms, we performed simultaneous single-cell RNA and ATAC sequencing on the
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