Evidence map›Paper›PMID 40950056›Full record

ArticlebioRxiv : the preprint server for biology2025

An electrostatic repulsion model of centromere organisation.

Caelan Bell, Lifeng Chen, M Julia Maristany, Claudia Blaukopf, Huabin Zhou, Jan Huertas, Jose I Perez Lopez, Christoph C H Langer, Thomas L Steinacker, Nikki Schütte and 6 more

Abstract readPreprint
PubMed Full text at PMC Publisher
In one paragraph

Article in bioRxiv : the preprint server for biology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors.

Caelan BellInstitute of Molecular Biotechnology of the Austrian Academy of Sciences (IMBA), Vienna BioCenter, 1030 Vienna, Austria.
Lifeng ChenMarine Biological Laboratory Chromatin Collaborative, Marine Biological Laboratory, Woods Hole, MA 02543, USA.ORCID 0000-0002-9866-8353
M Julia MaristanyMarine Biological Laboratory Chromatin Collaborative, Marine Biological Laboratory, Woods Hole, MA 02543, USA.
Claudia BlaukopfInstitute of Molecular Biotechnology of the Austrian Academy of Sciences (IMBA), Vienna BioCenter, 1030 Vienna, Austria.
Huabin ZhouMarine Biological Laboratory Chromatin Collaborative, Marine Biological Laboratory, Woods Hole, MA 02543, USA.ORCID 0000-0002-7788-0806
Jan HuertasMarine Biological Laboratory Chromatin Collaborative, Marine Biological Laboratory, Woods Hole, MA 02543, USA.
Jose I Perez LopezMarine Biological Laboratory Chromatin Collaborative, Marine Biological Laboratory, Woods Hole, MA 02543, USA.
Christoph C H LangerInstitute of Molecular Biotechnology of the Austrian Academy of Sciences (IMBA), Vienna BioCenter, 1030 Vienna, Austria.
Thomas L SteinackerInstitute of Molecular Biotechnology of the Austrian Academy of Sciences (IMBA), Vienna BioCenter, 1030 Vienna, Austria.
Nikki SchütteInstitute of Molecular Biotechnology of the Austrian Academy of Sciences (IMBA), Vienna BioCenter, 1030 Vienna, Austria.
Lynda K DoolittleDepartment of Biophysics and Howard Hughes Medical Institute, University of Texas Southwestern Medical Center, Dallas, TX 75390, USA.
Jorge R EspinosaYusuf Hamied Department of Chemistry, University of Cambridge, Cambridge CB2 1EW, UK.
Sy ReddingMarine Biological Laboratory Chromatin Collaborative, Marine Biological Laboratory, Woods Hole, MA 02543, USA.
Rosana Collepardo-GuevaraMarine Biological Laboratory Chromatin Collaborative, Marine Biological Laboratory, Woods Hole, MA 02543, USA.ORCID 0000-0003-1781-7351
Michael K RosenMarine Biological Laboratory Chromatin Collaborative, Marine Biological Laboratory, Woods Hole, MA 02543, USA.ORCID 0000-0002-0775-7917
Daniel W GerlichInstitute of Molecular Biotechnology of the Austrian Academy of Sciences (IMBA), Vienna BioCenter, 1030 Vienna, Austria.ORCID 0000-0003-1637-3365

Funding

Physical determinants of DNA recognition and genome organization in crowded environmentsR35GM147477 · NIGMS · UNIV OF MASSACHUSETTS MED SCH WORCESTER · PI Sy Redding · 2022 to 2026
$2.1M
Cell Organization Through Phase Separation: Mechanisms, Functions and DiseaseR35GM141736 · NIGMS · UT SOUTHWESTERN MEDICAL CENTER · PI ROSEN, MICHAEL K · 2021 to 2025
$1.8M
NIGMS NIH HHS R35 GM141736NIGMS NIH HHS R35 GM147477
6 · The paper itself

Abstract

During cell division, chromosomes reorganise into compact bodies in which centromeres localise precisely at the chromatin surface

Identifiers

PMID40950056
PMCPMC12424837

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.