Evidence map›Paper›PMID 40950039›Full record

ArticlebioRxiv : the preprint server for biology2025

Spontaneous peripheral oxygen desaturation and apnea events in mice vary by strain and inspired oxygen level.

Hardik Kalra, Anastasiia Vasileva, Charles R Jedlicka, Mikhail Vasilyev, Michelle A Buckman, Zishan Zhang, Brian K Gehlbach, Junjie Liu, Lara R DeRuisseau, Mark W Chapleau and 3 more

Abstract readPreprint
In one paragraph

Article in bioRxiv : the preprint server for biology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Hardik KalraDepartment of Internal Medicine, Iowa City, IA.
Anastasiia VasilevaDepartment of Internal Medicine, Iowa City, IA.
Charles R JedlickaDepartment of Health, Sport, and Human Physiology, Iowa City, IA.
Mikhail VasilyevDepartment of Internal Medicine, Iowa City, IA.
Michelle A BuckmanDepartment of Internal Medicine, Iowa City, IA.
Zishan ZhangDepartment of Internal Medicine, Iowa City, IA.
Brian K GehlbachDepartment of Neurology University of Iowa, Iowa City, IA.
Junjie LiuDepartment of Neurology University of Iowa, Iowa City, IA.
Lara R DeRuisseauDepartment of Basic Sciences, University of Health Sciences and Pharmacy, St. Louis, MO 63110.
Mark W ChapleauDepartment of Internal Medicine, Iowa City, IA.
Patrick J BrehenyDepartment of Biostatistics, Iowa City, IA 52242 USA.
Michael H TomassonDepartment of Internal Medicine, Iowa City, IA.
Melissa L BatesDepartment of Internal Medicine, Iowa City, IA.

Funding

Heart and vascular responses across the lifespan in Ts65Dn mice, a model of Down syndromeR21HD099573 · NICHD · SYRACUSE UNIVERSITY · PI DERUISSEAU, LARA ROBERTS · 2020 to 2021
$777k
Impact of chronic intermittent hypoxia on the bone marrowR56HL152365 · NHLBI · UNIVERSITY OF IOWA · PI BATES, MELISSA LOWE · 2020 to 2020
$385k
NHLBI NIH HHS R56 HL152365NICHD NIH HHS R21 HD099573
6 · The paper itself

Abstract

Mouse models of chronic intermittent hypoxia are widely used in research to understand the role of sleep apnea in disease pathogenesis. Mice exposed to periodic reductions in F

Indexed as

hypoxialight/darkoximetryplethysmographyventilation

Identifiers

PMID40950039
PMCPMC12424765

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.