Evidence map›Paper›PMID 40950003›Full record

ArticlebioRxiv : the preprint server for biology2025

Characterizing the role of RSD-6 in the biogenesis of virus-derived small interfering RNAs and the modulation of viral pathogenesis.

Krishna Dahal, Mingli Xia, Jinfeng Lu, Teng Yan, Rui Lu

Abstract readPreprint
PubMed Full text at PMC Publisher
In one paragraph

Article in bioRxiv : the preprint server for biology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

5 authors.

Krishna DahalDepartment of Biological Sciences, Louisiana State University, Baton Rouge, LA 70803.
Mingli XiaDepartment of Biological Sciences, Louisiana State University, Baton Rouge, LA 70803.
Jinfeng LuThe Taub Institute for Research on Alzheimer's Disease and the Aging Brain, Gertrude H. Sergievsky Center, Department of Neurology, College of Physicians and Surgeons, Columbia University, The New York Presbyterian Hospital, New York, NY 10032, USA.
Teng YanCurrent address: Key Laboratory for Northern Urban Agriculture of Ministry of Agriculture and Rural Affairs, Beijing University of Agriculture, Beijing 102206, China.
Rui LuDepartment of Biological Sciences, Louisiana State University, Baton Rouge, LA 70803.

Funding

In-depth study of antiviral RNA silencing in Caenorhabditis elegansR01GM119012 · NIGMS · LOUISIANA STATE UNIV A&M COL BATON ROUGE · PI LU, RUI · 2017 to 2021
$1.4M
Negative regulation of human antiviral RNAi by PACTR03AI171860 · NIAID · LOUISIANA STATE UNIV A&M COL BATON ROUGE · PI LU, RUI · 2023 to 2024
$148k
NIAID NIH HHS R03 AI171860NIGMS NIH HHS R01 GM119012
6 · The paper itself

Abstract

Small interfering RNAs (siRNAs) produced through the processing of viral double-stranded RNAs mediate potent antiviral RNA interference (RNAi) in eukaryotes. In

Identifiers

PMID40950003
PMCPMC12424992

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.