Evidence map›Paper›PMID 40949947›Full record

ArticlebioRxiv : the preprint server for biology2025

Limited generalizability of dynamic fMRI correlates of adolescent rumination.

Isaac N Treves, Madelynn S Park, Jamaal Spence, Nigel Jaffe, Kristina Pidvirny, Anna O Tierney, Aaron K Kucyi, John D E Gabrieli, Randy P Auerbach, Christian A Webb

Abstract readPreprint
PubMed Full text at PMC Publisher
In one paragraph

Article in bioRxiv : the preprint server for biology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

10 authors.

Isaac N TrevesMcGovern Institute for Brain Research, Massachusetts Institute of Technology, Cambridge, MA.ORCID 0000-0001-7802-6145
Madelynn S ParkMcGovern Institute for Brain Research, Massachusetts Institute of Technology, Cambridge, MA.
Jamaal SpenceDepartment of Psychiatry, Columbia University, New York, NY, USA.
Nigel JaffeDepartment of Psychiatry, Harvard Medical School, Harvard University.
Kristina PidvirnyDepartment of Psychiatry, Harvard Medical School, Harvard University.
Anna O TierneyDepartment of Psychiatry, Harvard Medical School, Harvard University.
Aaron K KucyiDepartment of Psychological & Brain Sciences, Drexel University, Philadelphia, PA.ORCID 0000-0001-6707-0028
John D E GabrieliMcGovern Institute for Brain Research, Massachusetts Institute of Technology, Cambridge, MA.
Randy P AuerbachDepartment of Psychiatry, Columbia University, New York, NY, USA.
Christian A WebbCenter for Depression, Anxiety, and Stress Research, McLean Hospital, Belmont, MA.ORCID 0000-0002-8310-4539

Funding

Supplemental: Neural and cognitive propensity for trait rumination in adolescents: a multimodal study with ecological momentary assessments and MRIR01AT011002 · NCCIH · MCLEAN HOSPITAL · PI WEBB, CHRISTIAN ANTHONY · 2021 to 2025
$3.4M
Predicting the onset of depression in at-risk adolescents from endophenotype profilesR01MH116969 · NIMH · MCLEAN HOSPITAL · PI WEBB, CHRISTIAN ANTHONY · 2019 to 2024
$2.8M
Examining Reward-Related Predictors and Mechanisms of Change in BA Treatment for Anhedonic AdolescentsK23MH108752 · NIMH · MCLEAN HOSPITAL · PI WEBB, CHRISTIAN ANTHONY · 2015 to 2018
$703k
NCCIH NIH HHS R01 AT011002NIMH NIH HHS K23 MH108752NIMH NIH HHS R01 MH116969
6 · The paper itself

Abstract

Rumination, or perseverative negative self-referential thinking, is a hallmark of depression. In adults, a dynamic resting-state fMRI model of trait rumination was recently identified through predictive modelling. In adolescents, a development period during which rumination and depression increase, the neurobiological correlates of ruminative thinking are less clear. In the current preregistered study, we examine dynamic connectivity correlates of self-reported rumination in the largest sample of adolescents to date (

Identifiers

PMID40949947
PMCPMC12424793

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.