Evidence map›Paper›PMID 40949932›Full record

ReviewWorld journal of cardiology2025

Relationship between genotype and clinical phenotype of hypertrophic cardiomyopathy.

Lan-Lan Zhang, Bo Wang, Jing Wang, Jia Zhao, Li-Wen Liu

Abstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in World journal of cardiology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Lan-Lan ZhangDepartment of Ultrasound, Xijing Hypertrophic Cardiomyopathy Center, Fourth Military Medical University, Xi'an 710000, Shaanxi Province, China.
Bo WangDepartment of Ultrasound, Xijing Hypertrophic Cardiomyopathy Center, Fourth Military Medical University, Xi'an 710000, Shaanxi Province, China.
Jing WangDepartment of Ultrasound, Xijing Hypertrophic Cardiomyopathy Center, Fourth Military Medical University, Xi'an 710000, Shaanxi Province, China.
Jia ZhaoDepartment of Ultrasound, Xijing Hypertrophic Cardiomyopathy Center, Fourth Military Medical University, Xi'an 710000, Shaanxi Province, China.
Li-Wen LiuDepartment of Ultrasound, Xijing Hypertrophic Cardiomyopathy Center, Fourth Military Medical University, Xi'an 710000, Shaanxi Province, China. liuliwen@fmmu.edu.cn.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Hypertrophic cardiomyopathy (HCM) is the most common genetic cardiovascular disease, mostly inherited in an autosomal dominant manner. It is a global heart disease with complex clinical phenotypes and gene expression. The prevalence rate in the population is 1:500-1:200. This article mainly introduces the diagnostic criteria, pathological manifestations, and genetic basis of HCM, which is the leading cause of sudden death in adolescents and athletes due to exercise, with 60%-70% showing familial clustering. It also discusses the latest progress in the relationship between different genotypes and clinical phenotypes of HCM patients.

Indexed as

GenotypeHypertrophic cardiomyopathyPhenotypeSarcomereThick myofilamentThin myofilament

Identifiers

PMID40949932
PMCPMC12426981

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.