Evidence map›Paper›PMID 40949811›Full record

ArticleHCA healthcare journal of medicine2025

Brown Umbilical Nodule: A Case of Primary Cutaneous Endometriosis.

Richard G Bindernagel, Aleia Boccardi, Taylor C Jindia, Parth Patel, Jaimie Bryan, Addie Walker, Summer Moon, Richard Miller

Abstract readCase Reports
In one paragraph

Article in HCA healthcare journal of medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Richard G BindernagelHCA Florida Largo Hospital, Largo, Florida.
Aleia BoccardiJohn's Episcopal Hospital, Far Rockaway, New York.
Taylor C JindiaTrinity Health, Ypsilanti, Michigan.
Parth PatelHonorHealth, Scottsdale, Arizona.
Jaimie BryanBay Dermatology & Cosmetic Surgery, Largo, Florida.
Addie WalkerOschner Medical Center, New Orleans, Louisiana.
Summer MoonHCA Florida Largo Hospital, Largo, Florida.
Richard MillerHCA Florida Largo Hospital, Largo, Florida.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Endometriosis is a common condition in which endometrial glands and stroma are implanted outside the uterine cavity. Rarely, the skin can be involved. Case Presentation: We describe a case of a 41-year-old woman who presented to the dermatology clinic complaining of a brown umbilical nodule with slight erythema. It was occasionally painful and hemorrhagic. She denied a history of endometriosis and abdominal surgeries. A shave biopsy of the nodule was consistent with a diagnosis of cutaneous endometriosis. The patient was referred to her gynecologist for further evaluation and treatment. Conclusion: This unique case demonstrates primary cutaneous endometriosis in the umbilicus of a female patient. Cutaneous endometriosis can be classified as primary or secondary. Primary cutaneous endometriosis is rarer and has an unclear etiology, developing seemingly spontaneously without history of surgical interventions. Secondary cutaneous endometriosis typically arises within surgical scars following abdominal operations, which is believed to be a result of iatrogenic implantation of endometrial cells. Definitive treatment involves surgery. This case highlights the importance of considering cutaneous endometriosis in the differential diagnosis of a female patient with painful and intermittently hemorrhagic skin nodules.

Indexed as

case reportscutaneous endometriosisendometriosisumbilical noduleumbilicus

Identifiers

PMID40949811
PMCPMC12425406

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.