ArticleFrontiers in surgery2025
High-frequency ultrasound combined with shear wave elastography to evaluate the efficacy of lymphaticovenular anastomosis in patients with secondary lymphedema.
Article in Frontiers in surgery, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
2 citing papers in PubMed.
- Do not mistake symptomatic improvement for disease modification: therapeutic endpoints in secondary lower-extremity lymphedema require inflammation-fibrosis anchoring.Frontiers in immunology · 2026Review
- Layer-Specific Assessment of Dermal Thickness and Stiffness Using Shear Wave Elastography in Gynecologic Cancer-Related Lower-Limb Lymphedema: An Exploratory Cross-Sectional Study.International journal of general medicine · 2026Article
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Authors and funding
7 authors.
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Abstract
Purpose: High-frequency ultrasound combined with shear wave elastography (SWE) was used to evaluate the efficacy of lymphaticovenular anastomosis (LVA) in treating secondary lymphedema. Materials and methods: This study included 40 patients with secondary lymphedema who underwent LVA at the Department of Vascular Surgery, Henan Provincial People's Hospital, from October 2023 to October 2024. Limb circumference measurements, bioelectrical impedance analysis (BIA), and high-frequency ultrasound combined with SWE were conducted before and after treatment. Changes in subcutaneous echo-free space (SEFS) grading and elastic parameters were analyzed pre- and post-treatment. Results: Following LVA, the percentage of excess volume (PEV) and the extracellular water/total body water (ECW/TBW) ratio in the affected limb significantly decreased ( Conclusion: The reduction in SEFS in the affected limb after LVA, along with the decreased SWV in the dermis and increased SWV in the subcutaneous tissue layer, suggests that LVA effectively reduces lymphatic fluid retention across all tissue layers. This provides novel ultrasonographic evidence for assessing and refining treatment efficacy and follow-up.
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