Evidence map›Paper›PMID 40949677›Full record

ReviewAnnals of translational medicine2025

Artificial intelligence-driven diagnosis of acute thoracic aortic dissection: integrating imaging, biomarkers, and clinical workflows-a narrative review.

Eunice Man Ki Lo, Sisi Chen, Randolph Hung Leung Wong

Abstract readReview
In one paragraph

Review in Annals of translational medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Eunice Man Ki LoDivision of Cardiothoracic Surgery, Department of Surgery, The Chinese University of Hong Kong, Hong Kong, China.
Sisi ChenDivision of Cardiothoracic Surgery, Department of Surgery, The Chinese University of Hong Kong, Hong Kong, China.
Randolph Hung Leung WongDivision of Cardiothoracic Surgery, Department of Surgery, The Chinese University of Hong Kong, Hong Kong, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background and Objective: Patients presenting to the emergency department with acute thoracic aortic dissection (ATAD) often experience chest pain that requires urgent intervention. However, other chest pain-related emergencies, such as acute coronary syndrome (ACS) and acute pulmonary embolism (PE), are far more common and frequently overshadow ATAD. This disparity leads to a high rate of ATAD misdiagnosis. Recent advancements in artificial intelligence (AI) have led to the development of various models utilizing imaging modalities and biomarkers to enable rapid triage and diagnosis of ATAD in emergency settings. This article aims to evaluate the performance and clinical significance of these AI models within the context of clinical workflows. Methods: We performed literature searches in PubMed, Scopus, and Web of Science to identify relevant studies published between 2015 and 2025, with the focus of the differentiation of ATAD patients from other chest pain-related conditions in emergency settings, with the application of AI. Key Content and Findings: Eighteen studies were retrieved from the past ten years, highlighting a significant knowledge gap in the field of translational medicine. The discussion included an overview of AI-powered models for ATAD diagnosis, as well as guidelines on current clinical workflows and the application of AI in clinical settings. Conclusions: This article offers a detailed review of AI models developed for the screening and diagnosis of ATAD. It highlights not only the performance of these technologies but also their clinical importance in facilitating timely interventions for high-risk patients. Looking forward, we anticipate a future where AI and deep learning (DL)-driven ATAD diagnostic models will play a pivotal role in optimizing ATAD clinical management.

Indexed as

acute thoracic aortic dissection (ATAD)aortic dissection (AD)Artificial intelligence (AI)deep learning (DL)machine learning (ML)

Identifiers

PMID40949677
PMCPMC12432618

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.