Evidence map›Paper›PMID 40949637›Full record

ArticleJournal of the colleges of medicine of South Africa2024

Stage of presentation and survival rates of head and neck cancer in Western Cape, South Africa.

Simon M Honnet, Oskar Edkins, Sameera Dalvie, Julie A Wetter, Justin Harvey, Johannes J Fagan

Abstract read
In one paragraph

Article in Journal of the colleges of medicine of South Africa, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Simon M HonnetDepartment of Surgery, Division of Otolaryngology, Faculty of Health Sciences, University of Cape Town, Cape Town, South Africa.ORCID https://orcid.org/0000-0001-9592-5388
Oskar EdkinsDepartment of Otolaryngology, Head and Neck Surgery, Townsville University Hospital, Townsville, Australia.ORCID https://orcid.org/0009-0003-0724-530X
Sameera DalvieDepartment of Radiation Oncology, Division of Radiation Medicine, Faculty of Health Sciences, University of Cape Town, Cape Town, South Africa.ORCID https://orcid.org/0000-0003-4031-5480
Julie A WetterDepartment of Radiation Oncology, Division of Radiation Medicine, Faculty of Health Sciences, University of Cape Town, Cape Town, South Africa.ORCID https://orcid.org/0000-0002-5401-7719
Justin HarveyDepartment of Statistics and Actuarial Science, Faculty of Economics and Management Science, Stellenbosch University, Stellenbosch, South Africa.ORCID https://orcid.org/0000-0002-8101-373X
Johannes J FaganDepartment of Surgery, Division of Otolaryngology, Faculty of Health Sciences, University of Cape Town, Cape Town, South Africa.ORCID https://orcid.org/0000-0001-7924-7265

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: The Western Cape province in South Africa has a high age-standardised mortality from cancer. Most literature reports significantly poorer access to healthcare, more advanced cancers and worse survival for rural and remote populations. This study investigates if significant disparities exist with regard to stage at presentation and overall survival of patients with head and neck cancer (HNC) between geographical areas within the Western Cape province in South Africa. Methods: A retrospective chart review was conducted on all patients managed at the Combined ENT & Head and Neck Oncology clinic at Groote Schuur from January 2010 to December 2014. Ethics approval was granted by the University of Cape Town Human Research Ethics Committee (HREC, 351-2017). Results: Although we observed no significant difference in TNM clinical stages or overall survival between metropolitan and remote patients, there were statistically and clinically significant differences in terms of both stages of HNC and overall survival between some individual metropolitan and remote areas. The remote area of Eden had a median overall survival of more than 6 months less than that of the Southern subdistrict of the City of Cape Town. Conclusion: Differences in HNC stages and overall survivals between some subdistricts of the City of Cape Town and remote areas are not only statistically significant but also clinically relevant. Contribution: This article highlights the need to improve on diagnostic and referral pathways for management of patients with HNC in the Western Cape.

Indexed as

cancerhead and neckmetropolitanoverall survivalremotestageWestern Cape

Identifiers

PMID40949637
PMCPMC12376214

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.