Evidence map›Paper›PMID 40949634›Full record

ArticleJournal of the colleges of medicine of South Africa2024

Gardasil

Shavina Frank, Jessica K McGuire, Fiona Kabagenyi, Shazia Peer

Erratum issuedAbstract read
In one paragraph

Article in Journal of the colleges of medicine of South Africa, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

4 authors.

Shavina FrankDepartment of Otorhinolaryngology, Faculty of Health Sciences, University of Cape Town, Cape Town, South Africa.ORCID https://orcid.org/0000-0003-3039-5608
Jessica K McGuireDepartment of Otorhinolaryngology, Faculty of Health Sciences, University of Cape Town, Cape Town, South Africa.ORCID https://orcid.org/0000-0001-6816-8959
Fiona KabagenyiDepartment of Ear, Nose and Throat, Faculty of Medicine, Makerere University, Kampala, Uganda.ORCID https://orcid.org/0000-0002-2287-2809
Shazia PeerDepartment of Otorhinolaryngology, Faculty of Health Sciences, University of Cape Town, Cape Town, South Africa.ORCID https://orcid.org/0000-0001-6326-1193

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Juvenile onset recurrent respiratory papillomatosis (JoRRP) is an incurable condition caused by human papilloma virus (HPV) types 6 and 11, often requiring repeated surgeries and in severe cases, tracheostomy. This imposes a significant socioeconomic burden on patients and families. Gardasil Methods: We conducted a retrospective review at Red Cross War Memorial Children's Hospital from January 2015 to June 2022 on histologically confirmed JoRRP cases. Age at diagnosis, baseline and post-dosing Derkay-Coltrera (DC) scores (disease severity measure), inter-surgical intervals and tracheostomy, were collected. Results: Twenty-five of 30 confirmed cases were included. Average age at diagnosis was 60 months (about 5 years old), with HPV Type 6 in 40% and Type 11 in 48% of patients. All patients received at least one Gardasil Conclusion: This is the first study in Southern Africa highlighting Gardasil Contribution: This suggests that Gardasil

Indexed as

Derkay-Coltrera scoreGardasil-4Gardasil-4®human papilloma virusjuvenile-onset recurrent respiratory papillomatracheostomyupper airway obstructionvaccine

Identifiers

PMID40949634
PMCPMC12376258

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.