Evidence map›Paper›PMID 40949528›Full record

ReviewJGH open : an open access journal of gastroenterology and hepatology2025

Trends and Demographics of Vascular Intestinal Diseases-Related Mortality Among Adults Living in United States From 1999 to 2020; A CDC Wonder Analysis.

Muhammad Shahzad, Kanz Ul Eman Maryam, Ali Hashim, Amna Zaman Khan, Muhammad Abdullah Ali, Ahmed Yar Khan, Muhammad Younas, Syeda Sundus Shah Bokhari, Wania Khalid, Farah Shahzad and 6 more

Abstract readReview
In one paragraph

Review in JGH open : an open access journal of gastroenterology and hepatology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Observational
  3. Review
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors.

Muhammad ShahzadFoundation University Medical College Islamabad Pakistan.ORCID https://orcid.org/0009-0004-8622-5397
Kanz Ul Eman MaryamFoundation University Medical College Islamabad Pakistan.
Ali HashimAl-Aleem Medical College University of Health Sciences Lahore Pakistan.
Amna Zaman KhanAl-Aleem Medical College University of Health Sciences Lahore Pakistan.
Muhammad Abdullah AliKhyber Medical College Peshawar Pakistan.ORCID https://orcid.org/0009-0002-3199-7862
Ahmed Yar KhanAl-Aleem Medical College University of Health Sciences Lahore Pakistan.
Muhammad YounasGomal Medical College, Dera Ismail Khan Pakistan.
Syeda Sundus Shah BokhariAyub Medical College Abbottabad Pakistan.
Wania KhalidFoundation University Medical College Islamabad Pakistan.
Farah ShahzadKhyber Medical College Peshawar Pakistan.
Kashmala ZiaDepartment of Anatomy Foundation University Medical College Islamabad Pakistan.
Ali HassanFauji Foundation Hospital Rawalpindi Pakistan.
Muhammad Uzair Khan NiaziDepartment of Anatomy Foundation University Medical College Islamabad Pakistan.
Fahad RahmanKhyber Medical College Peshawar Pakistan.
Saad Ahmed WaqasDow University of Health Sciences Karachi Pakistan.ORCID https://orcid.org/0009-0008-9051-6081
Raheel AhmedImperial College London National Heart and Lung Institute London UK.ORCID https://orcid.org/0000-0003-2814-7314

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: Vascular intestinal disorders (VID), including mesenteric ischemia, ischemic colitis, and intestinal angiodysplasia, have a global incidence of 8.11/100 000/year and a mortality of 1.26/100 000/year (15.5% death rate), rising from ~1% to ~3% in childhood to ~50% after 95 years. In the US, the incidence of acute vascular insufficiency of the intestine (AVII) is rising, warranting detailed trend analysis. Methods: CDC WONDER death certificates (1999-2020) for adults > 25 years were analyzed using ICD-10 code N55. Age-adjusted mortality rates (AAMRs) per 100 000 were stratified by year, sex, race/ethnicity, and region. Joinpoint Regression (v5.2.0) calculated annual percent changes (APCs); significance was defined as Results: Overall AAMR declined from 9.35 (1999) to 5.81 (2020). Women had higher AAMRs (7.63; 95% CI: 7.6-7.66) than men (6.5; 95% CI: 6.49-6.56). By race/ethnicity, AAMRs were highest in NH American Indian (7.89; 95% CI: 7.57-8.21), NH Black (7.84; 95% CI: 7.75-7.9), NH White (7.25; 95% CI: 7.22-7.28), Hispanic (5.91; 95% CI: 5.83-6), and NH Asian (3.59; 95% CI: 3.5-3.68). Micropolitan areas had higher AAMRs (7.92) than metropolitan (6.99). Regional AAMRs were highest in the Midwest (7.7; 95% CI: 7.65-7.75), followed by South (7.17; 95% CI: 7.13-7.21), West (7.02; 95% CI: 6.96-7.07), and Northeast (6.85; 95% CI: 6.79-6.9). Kentucky had the highest state AAMR (9.67; 95% CI: 9.43-9.9), Hawaii the lowest (4.59; 95% CI: 4.31-4.87). Oklahoma, Rhode Island, Tennessee, West Virginia, and Wyoming ranked in the top 90th percentile. Conclusion: Despite an overall decline, VID mortality remains high among women, NH American Indians, rural areas, and the Midwest-underscoring the need for targeted interventions.

Indexed as

mortalitytrendsvascular intestinal disorders (VID)

Identifiers

PMID40949528
PMCPMC12426610

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.