ArticleIndian journal of surgical oncology2025
Utility of the Clinical and Radiological Features in the Management of Bethesda 3 and 4 Thyroid Nodules.
Article in Indian journal of surgical oncology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
- The Importance of the Taller-than-Wide Feature and the Dimensions of Focal Thyroid Lesions in Assessing the Risk of Malignancy.Diagnostics (Basel, Switzerland) · 2026Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Deciding the right treatment strategy for patients with Bethesda 3 and 4 fine needle aspiration cytology (FNAC) reports may be challenging. The reported risk of malignancy (ROM) and those from high-volume institutes may not be identical. The cost of molecular testing and its unavailability for routine use limits its utility in decision-making. In this study, we included all patients diagnosed at our institute with Bethesda 3 and 4 thyroid nodules on FNAC between January 2012 and December 2021. We identified the risk of malignancy for these patients along with other factors that could help identify the possibility of malignancy in these thyroid nodules. We utilised the clinical (C), ultrasound features (U), and the Bethesda category (T) to derive the CUT score and derive a cut-off value beyond which malignancy could be predicted. A total of 359 patients were included in the study. The ROM for the Bethesda 3 thyroid nodule was 77.7% (167/215), and that for the Bethesda 4 thyroid nodule was 76.4% (110/144). On multivariate analysis, nodules taller than wider [0.006, 7.662 (1.806-32.5)], male gender [0.024, 2.359 (1.119-4.976)], and the presence of microcalcification [0.004, 2.328 (1.319-4.109)] were found to be significant for the presence of malignancy in the final histopathology. The CUT score > 8.875 was associated with malignancy in the final histopathology. Various clinical and radiological factors may be useful to identify the nodules harbouring malignancy and facilitate appropriate management. The rate of malignancy in Bethesda 3 and 4 nodules among those who underwent surgery in our cohort was higher. Supplementary Information: The online version contains supplementary material available at 10.1007/s13193-024-02167-7.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.