Evidence map›Paper›PMID 40949397›Full record

ArticleWorld journal of gastrointestinal surgery2025

Morphomics in esophageal cancer: Validation and association with muscular and cardiorespiratory fitness.

Watson Hua-Sheng Tseng, Shu-Chun Huang, Stewart C Wang, Jules Lin, Peng Zhang, Yu-Chen Liu, Yin-Kai Chao, Chien-Hung Chiu

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Article in World journal of gastrointestinal surgery, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

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1citing papers in PubMed
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1 · What the graph read from it

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3 · Its place in the literature

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1 citing paper in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

8 authors.

Watson Hua-Sheng TsengDepartment of Medical Education, Chang Gung Memorial Hospital at Linkou, Taoyuan 33305, Taiwan.
Shu-Chun HuangDepartment of Physical Medicine and Rehabilitation, New Taipei Municipal Tucheng Hospital, Chang Gung Memorial Hospital, New Taipei City 236043, Taiwan.
Stewart C WangDepartment of Surgery, University of Michigan, Ann Arbor, MI 48109, United States.
Jules LinSection of Thoracic Surgery, University of Michigan, Ann Arbor, MI 48109, United States.
Peng ZhangDepartment of Surgery, University of Michigan, Ann Arbor, MI 48109, United States.
Yu-Chen LiuDepartment of Physical Medicine & Rehabilitation, Chang Gung Memorial Hospital at Linkou, Taoyuan 33305, Taiwan.
Yin-Kai ChaoDivision of Thoracic Surgery, Chang Gung Memorial Hospital at Linkou, Taoyuan 33305, Taiwan.
Chien-Hung ChiuDivision of Thoracic Surgery, Chang Gung Memorial Hospital at Linkou, Taoyuan 33305, Taiwan. happy9000000@gmail.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundMorphomics, a computed tomography-based body composition assessment, helps predicting esophageal cancer outcomes, but its link to bioelectrical impedance analysis (BIA) and functional assessments such as hand grip strength (HGS) and cardiopulmonary exercise testing (CPET) remains unclear.

aimTo investigate correlations between morphomics and BIA, HGS, CPET, and assess its ability to predict low cardiorespiratory fitness (CRF).

methodsFifty esophageal cancer patients underwent multi-level morphomics, BIA, HGS, and CPET. Correlations were analyzed using heatmaps and scatter plots, and logistic regression assessed morphomic predictive value for low CRF.

resultsT11 is the only level with complete morphomic data, making it the most applicable. To ensure reliability, T11 and its adjacent levels, T10-12, were included in the subsequent analysis. Dorsal muscle group volume from T10-12 morphomics all correlated positively with BIA muscle components (

conclusionT11 morphomics shows strong correlation with BIA, HGS, and CPET, and may serve as a practical tool for preoperative risk assessment in esophageal cancer patients.

Indexed as

Bioelectrical impedance analysisBody compositionCardiopulmonary exercise testingComputed tomographyHand grip strengthMorphomics

Identifiers

PMID40949397
PMCPMC12427075

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