ArticleWorld journal of gastrointestinal surgery2025
Analysis of the clinical value of gemstone spectral computed tomography imaging in the preoperative assessment of colorectal cancer.
Article in World journal of gastrointestinal surgery, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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Abstract
backgroundThe diagnostic accuracy for detecting metastatic lymph nodes in colorectal cancer (CRC) remains suboptimal. To address this limitation, our study investigates the potential of gemstone spectral computed tomography imaging (GSI) to improve diagnostic accuracy in lymph node metastasis (LNM) assessment.
aimTo extensively investigate the clinical utility of GSI in the preoperative assessment of CRC.
methodsThe subject population included 200 patients with CRC who were admitted to Zibo Central Hospital from January 2022 to December 2023. All patients underwent dual-phase contrast-enhanced scans in the arterial and venous phases using GSI before surgical intervention. During the research, meticulous quantification was conducted regarding the number of patients with CRC with LNM as well as the exact count of metastatic lymph nodes. Moreover, for both metastatic and non-metastatic lymph nodes, the short diameter at the maximum cross-sectional area (covering the axial, sagittal, and coronal planes), morphological features (including manifestations such as margin blurring, aggregation, and enhancement), and spectral parameters in the arterial and venous phases [specifically iodine concentration (IC), normalized IC (NIC), and the slope of the spectral curve (λ
resultsThe area under the curve of GSI for diagnosing LNM in patients with CRC can reach 0.897, with sensitivity, specificity, and accuracy of 92.59%, 85.87%, and 89.50%, respectively. A total of 265 lymph nodes were analyzed from the 200 participants with CRC, with metastatic lymph nodes accounting for 56.60%. Compared with non-metastatic lymph nodes, the short diameters of metastatic lymph nodes in the axial, sagittal, and coronal planes were significantly increased, whereas the IC values in the arterial and venous phases, the NIC value in the arterial phase, and the λ
conclusionGSI exhibits substantial clinical significance in the preoperative assessment of CRC. Among the parameters assessed, the arterial-phase IC demonstrates the most outstanding diagnostic performance, effectively improving the diagnostic efficacy for preoperative LNM in CRC.
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